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http://dx.doi.org/10.5012/jkcs.2010.54.01.049

Design, Synthesis and Spectral Characterization of Novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides  

Kanagarajan, Vijayakumar (Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University)
Thanusu, Jayaraman (Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University)
Gopalakrishnan, Mannathusamy (Synthetic Organic Chemistry Laboratory, Department of Chemistry, Annamalai University)
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Abstract
A new series of novel 2-morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides 34-42 is synthesized by the condensation of 2-chloro-N-(4,6-diarylpyrimidin-2-yl)acetamides 25-33 with morpholine in the presence of anhydrous potassium carbonate. The synthesized compounds have been characterized by melting point, elemental analysis, MS, FT-IR, one-dimensional NMR ($^1H$ & $^{13}C$) spectroscopic data.
Keywords
2-Morpholino-N-(4,6-diarylpyrimidin-2-yl)acetamides; 4,6-Diarylpyrimidin-2-amines; Chloroacetylation; Morpholine; Synthesis;
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