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http://dx.doi.org/10.5012/jkcs.2007.51.4.352

3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene, A New Phenanthrene from Bulbophyllum Odoratissimum  

Chen, Ye-Gao (Department of Chemistry, Yunnan National University)
Xu, Jun-Ju (Department of Chemistry, Yunnan National University)
Yu, Hong (School of Life Science, Yunnan University)
Qing, Chen (Yunnan Key Laboratory of Pharmacology for Natural Products Research, Kunming Medical College)
Zhang, Yan-Li (Yunnan Key Laboratory of Pharmacology for Natural Products Research, Kunming Medical College)
Liu, Ying (Department of Chemistry, Yunnan National University)
Wang, Ji-Hua (Department of Chemistry, Yunnan National University)
Publication Information
Journal of the Korean Chemical Society / v.51, no.4, 2007 , pp. 352-355 More about this Journal
Abstract
A new phenanthrene derivative 3,7-dihydroxy-2,4,6-trimethoxyphenanthrene was isolated from the all plant of Bulbophyllum odoratissimum, and its structure was elucidated by extensive spectral studies and chemical transformation. The compound displayed cytotoxicity against the growth of human leukemia cell lines K562 and HL-60, human lung adenocarcinoma A549, human hepatoma BEL-7402 and human stomach cancer cell lines SGC-7901 with IC50 values of 14.23, 10.02, 3.42, 15.36 and 1.13 mg/ml respectively.
Keywords
Bulbophyllum odoratissimum; Orchidaceae; Phenanthrene; 3,7-Dihydroxy-2,4,6-trimethoxyphenanthrene; Cytotoxicity;
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