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http://dx.doi.org/10.5012/jkcs.2003.47.1.047

Partial Synthesis of Fibrostatins  

Kwan Hee Lee (School of Life and Food Science, Handong University)
Harold w. Moore (Department of Chemistry, Uniersity of California at Irvine)
Publication Information
Journal of the Korean Chemical Society / v.47, no.1, 2003 , pp. 47-58 More about this Journal
Abstract
Fibrosstatins, which were isolated from the culture broth of Streptomyces catanulae subsp. griseospora, are naphthoquinones which can work as alkylating agents. It is important to synthesize these quinone compounds for the study of their biological activities. In this paper, an efficient method, Hooker oxidation, to control the regiochemistry in the synthesis of fibrostatin B is reported.
Keywords
Hook Oxidation; Fibrostatin; Allkylating Agents; Quinones;
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