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http://dx.doi.org/10.5012/bkcs.2014.35.2.345

Synthesis of Vinyl Sulfone-tethered Proline Derivatives as Highly Selective Cathepsin S Inhibitors  

Kim, Mira (Department of Drug Discovery, Hanmi Research Center)
Jeon, Jiyoung (Department of Drug Discovery, Hanmi Research Center)
Baek, Jongouk (Department of Drug Discovery, Hanmi Research Center)
Choi, Jaeyul (Department of Drug Discovery, Hanmi Research Center)
Park, Eun Ju (Department of Drug Discovery, Hanmi Research Center)
Song, Jiyeon (Department of Drug Discovery, Hanmi Research Center)
Bang, Hyojeong (Department of Drug Discovery, Hanmi Research Center)
Suh, Kwee Hyun (Department of Drug Discovery, Hanmi Research Center)
Kim, Young Hoon (Department of Drug Discovery, Hanmi Research Center)
Kim, Jongmin (College of Pharmacy, Chung-Ang University)
Kim, Doran (College of Pharmacy, Chung-Ang University)
Min, Kyung Hoon (College of Pharmacy, Chung-Ang University)
Lee, Kwang-Ok (Department of Drug Discovery, Hanmi Research Center)
Publication Information
Bulletin of the Korean Chemical Society / v.35, no.2, 2014 , pp. 345-346 More about this Journal
Keywords
Cathepsin S inhibitor; Proline; Vinyl sulfone; Small molecule;
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13 Enzymatic assay for hCat S, hCat B and hCat K was performed using $SensoLyte^{(R)}$ 520 Cathepsin Activity Assay Kit from Anaspec, Inc.