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http://dx.doi.org/10.5012/bkcs.2014.35.1.98

Organocatalytic Asymmetric Michael Addition of 1,3-Cyclohexanedione to Benzylidenemalonitriles  

Suh, Chang Won (Department of Chemistry, Soonchunhyang University)
Kim, Dae Young (Department of Chemistry, Soonchunhyang University)
Publication Information
Bulletin of the Korean Chemical Society / v.35, no.1, 2014 , pp. 98-102 More about this Journal
Abstract
The organocatalytic enantioselective Michael addition reaction promoted by chiral binaphthyl-modified squaramide catalyst have been developed, allowing facile synthesis of the corresponding chiral 2-amino-4H-chromenes derivatives with excellent enantioselectivity (up to 99% ee). The method reported represents a practical entry for the preparation of chiral 2-amino-4H-chromenes derivatives.
Keywords
Asymmetric catalysis; Organocatalysis; Michael addition; 2-Amino-4H-chromenes;
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