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http://dx.doi.org/10.5012/bkcs.2013.34.2.394

Synthesis of N-Azaaryl Anilines: An Efficient Protocol via Smiles Rearrangement  

Xia, Shuai (College of Pharmaceutical Sciences, Southwest University)
Wang, Li-Ying (College of Pharmaceutical Sciences, Southwest University)
Sun, Heng-Zhi (College of Pharmaceutical Sciences, Southwest University)
Yue, Huan (College of Pharmaceutical Sciences, Southwest University)
Wang, Xiu-Hua (College of Pharmaceutical Sciences, Southwest University)
Tan, Jia-Lian (College of Pharmaceutical Sciences, Southwest University)
Wang, Yin (College of Pharmaceutical Sciences, Southwest University)
Hou, Di (College of Pharmaceutical Sciences, Southwest University)
He, Xiao-Yan (College of Pharmaceutical Sciences, Southwest University)
Mun, Ki-Cheol (College of Pharmaceutical Sciences, Southwest University)
Kumar, B. Prem (Department of Chemistry, Changwon National University)
Zuo, Hua (College of Pharmaceutical Sciences, Southwest University)
Shin, Dong-Soo (Department of Chemistry, Changwon National University)
Publication Information
Bulletin of the Korean Chemical Society / v.34, no.2, 2013 , pp. 394-398 More about this Journal
Abstract
An efficient process for the synthesis of N-azaaryl anilines via Smiles rearrangement as a tool. A variety of N-azaaryl anilines were generated by the reaction of substituted phenols, substituted anilines, aminopyridines and chloroacetyl chloride or pyridols, under base condition in good to excellent yields.
Keywords
Smiles rearrangement; N-Azaaryl anilines; Amine; Phenol; Synthesis;
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