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http://dx.doi.org/10.5012/bkcs.2013.34.10.2959

Deuterium Naturally Present in Solvent and Site-Specific Isotope Population of Deuterium-Enriched Solute  

Hwang, Ryeo Yun (Analysis Research Division, Daegu Center, Korea Basic Science Institute)
Han, Oc Hee (Analysis Research Division, Daegu Center, Korea Basic Science Institute)
Lee, Juhee (Analysis Research Division, Daegu Center, Korea Basic Science Institute)
Kim, Eun Hee (Ochang Campus, Korea Basic Science Institute)
Publication Information
Bulletin of the Korean Chemical Society / v.34, no.10, 2013 , pp. 2959-2962 More about this Journal
Abstract
As the concentration of aqueous $CD_3OH$ solutions was decreased, the OD peaks in $^2H$ NMR spectra grew relative to the $CD_3$ peaks. Isotope impurity for OH groups of $CD_3OH$ and deuterium naturally present in water contributed to the OD peaks. Using these peak area data, the site-specific isotope populations of isotope enriched chemicals were measured. In addition, the method using both $^1H$ and $^2H$ NMR spectroscopy was demonstrated with neat $CD_3OH$ to measure the site-specific isotope populations. The results indicate that although it represents only ~0.015% of hydrogen isotopes, the deuterium naturally present in solvents cannot be ignored, especially when the concentration of deuterium-enriched solutes is varied. Proton/deuteron exchange between methyl and methyl/hydroxyl groups was confirmed to be negligible, while that among hydroxyl groups was detectable.
Keywords
NMR spectroscopy; Deuterium; Isotopes; Alcohol; Proton exchange;
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