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http://dx.doi.org/10.5012/bkcs.2012.33.8.2647

Concise Synthetic Approaches to Naturally Occurring β-Hydroxypyranochalcones: First Total Synthesis of Purpurenone, Its Derivative, and Praecansone B  

Wang, Xue (School of Chemical Engineering, Yeungnam University)
Lee, Yong-Rok (School of Chemical Engineering, Yeungnam University)
Kim, Sung-Hong (Analysis Research Division, Daegu Center, Korea Basic Science Institute)
Publication Information
Bulletin of the Korean Chemical Society / v.33, no.8, 2012 , pp. 2647-2650 More about this Journal
Abstract
The total synthesis of biologically interesting ${\beta}$-hydroxypyranochalcones, purpurenone (1), its derivative 2, praecansone B (3), and pongapinone A (4) has been accomplished starting from commercially available 2,4-dihydroxyacetophenone or 6-methoxy-2,4-dihydroxyacetophenone in 3 steps by a convergent strategy through benzopyran formations, O-methylations, and coupling reactions.
Keywords
${\beta}$-Hydroxypyranochalcone; Purpurenone; Praecansone B; Pongapinone A; Benzopyran formation;
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