Browse > Article
http://dx.doi.org/10.5012/bkcs.2012.33.7.2247

Two New Bibenzyl Glucosides from Dendrobium chrysotoxum  

Dong, Fa-Wu (College of Life Sciences, Anhui University)
Luo, Huai-Rong (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences)
Wan, Qin-Li (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences)
Xu, Feng-Qing (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences)
Fan, Wei-Wei (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences)
Wang, Kai-Jin (College of Life Sciences, Anhui University)
Li, Ning (College of Life Sciences, Anhui University)
Hu, Jiang-Miao (State Key Laboratory of Phytochemistry and Plant Resource in West China, Kunming Institute of Botany, Chinese Academy of Sciences)
Publication Information
Abstract
Two new bibenzyl glucosides, 3,3',4',5-tetramethoxybibenzyl-4-O-${\beta}$-D-glucopyranoside (1) and 3,4,4',5-tetramethoxybibenzyl-3'-O-${\beta}$-D-glucopyranoside (2), together with five known ones, chrysotobibenzyl (3), erianin (4), chrysotoxine (5), gigantol (6) and tristin (7) were isolated from the stems of Dendrobium chrysotoxum. The structures of those compounds were elucidated by extensive spectroscopic analysis. Moreover, compounds 1-7 were assessed for inhibitory activity of two enzymes-AChE (acetylcholine esterase) and BChE (butyrylcholine esterase).
Keywords
Dendrobium chrysotoxum; Orchidaceae; Bibenzyl glucosides; AChE and BChE;
Citations & Related Records

Times Cited By Web Of Science : 0  (Related Records In Web of Science)
연도 인용수 순위
  • Reference
1 Ma, G. X.; Xu, G. J.; Xu, L. S.; Wang, Z. T.; Kickuchi, T. Acta Pharmaceutica Sinica 1994, 29, 763.
2 Ma, G. X.; Xu, G. J.; Xu, L. S.; Wang, Z. T.; Kickuchi, T. Acta Pharmaceutica Sinica 1996, 31, 222.
3 Wang, Z. T.; Fan, Y.; Wu, D. Z.; Yang, H.; Hu, Z. B.; Gong, Y. Q. European Journal of Cancer 2004, 40, 1554.   DOI   ScienceOn
4 Fulvia, O.; Francesca, P.; Barbara, B.; Giuliana, M. Carbohydrate Research 1997, 301, 95.   DOI
5 Sianne, S.; Zhou, B. N.; Thomas, E. G.; Jessica, L. S.; David, G. I. K. J. Nat. Prod. 2000, 63, 457.   DOI
6 Changeux, J. P.; Lena, C. J. Physiol. - Pari 1998, 92, 63.   DOI
7 Levey, A. I.; Edmunds, S. M.; Koliatsos, V.; Wiley, R. G.; Heilman, C. J. J. Neurosci. 1995, 15, 4077.
8 Efrat, G.; Yacov, A.; Donna, S. A.; Jeffrey, S.; Yaacov, H.; Marta, W. Molecular Pharmacology 2007, 71, 1610.   DOI
9 Pacher, T.; Seger, C.; Engelmeier, D. J. Nat. Prod. 2002, 65, 820.   DOI
10 Daniela, M. B.; Concetta, R.; Giuseppe, R. J. Nat. Prod. 2005, 68, 1099.   DOI   ScienceOn
11 Christian, Z.; Sandra, G.; Ernst, P. E.; Ongania, K. H.; Hermann, S. Phytochemistry 2006, 67, 2182.   DOI
12 Juneja, R. K.; Sharma, S. C.; Tandon, J. S. Phytochemistry 1987, 26, 1123.   DOI
13 Majumder, P. L.; Pal, S. Phytochemistry 1993, 32, 1561.   DOI
14 Ellman, G. L.; Courtney, K. D.; Andres, V. J.; Featherstone, R. M. Biochem. Pharmacol. 1961, 7, 88.   DOI   ScienceOn
15 Bao, X. S.; Shun, Q. S.; Chen, L. Z. The Medicinal Plants of Dendrobium (Shi-hu) in China, A Coloured Atlas; Fudan University and Shanghai Medical University Press: 2001; p 109.
16 Committee of the Pharmacopoeia of China, Pharmacopoeia of China, Part I; Chemistry and Industry Press: 2005; p 62.
17 Ma, G. X.; Wang, Z. T.; Xu, L. S.; Xu, G. J. Chinese J. Pharm. Sci. 1998, 7, 142.
18 Jiangsu New Medicinal University, Dictionary of Chinese Medicines; Shanghai Scientific and Technical Publishers: 1986; p 586.
19 Ye, Q. H.; Zhao, W. M.; Qin, G. W. In The Progress in Medicinal Chemistry; Peng, S. X., Ed.; Chemical Industry Press: 2002; p 113.