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http://dx.doi.org/10.5012/bkcs.2012.33.4.1310

Synthesis and Antibacterial Activity of Novel 2-Oxo-pyrrolidinyl Oxazolidinones  

Bhattarai, Deepak (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Lee, Sun-Hee (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Kim, Hyeong-Kyu (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Kang, Soon-Bang (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Pae, Ae-Nim (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Kim, Eunice Eun-Kyeong (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Oh, Taeg-Won (Department of Microbiology and the Brain Korea 21 Project for the Medical Sciences, Yonsei University College of Medicine)
Cho, Sang-Nae (Department of Microbiology and the Brain Korea 21 Project for the Medical Sciences, Yonsei University College of Medicine)
Keum, Gyo-Chang (Center for Neuro-Medicine, Brain Science Institute, Korea Institute of Science and Technology)
Publication Information
Bulletin of the Korean Chemical Society / v.33, no.4, 2012 , pp. 1310-1316 More about this Journal
Abstract
Novel antibacterial oxazolidinones bearing pyrrolidinone ring system at the C-5 side chain were synthesized and their in vitro antibacterial activities were evaluated. Most of the synthesized oxazolidinones showed good antibacterial activity against the Gram-positive and Gram-negative bacteria tested.
Keywords
Pyrrolidinone; Oxazolidinone; Antimicrobial activity;
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