Browse > Article
http://dx.doi.org/10.5012/bkcs.2012.33.2.657

Biological Toxicity Changes of Mercaptoacetic Acid and Mercaptopropionic Acid Upon Coordination onto ZnS:Mn Nanocrystal  

Kong, Hoon-Young (Department of Molecular Biology, Institute of Nanosensor and Biotechnology, Dankook University)
Hwang, Cheong-Soo (Department of Chemistry and, Institute of Nanosensor and Biotechnology, Dankook University)
Byun, Jong-Hoe (Department of Molecular Biology, Institute of Nanosensor and Biotechnology, Dankook University)
Publication Information
Bulletin of the Korean Chemical Society / v.33, no.2, 2012 , pp. 657-662 More about this Journal
Abstract
Mercaptoacetic acid (MAA) and mercaptopropionic acid (MPA) capped ZnS:Mn nanocrystals were synthesized and their physical characteristics were examined by XRD, HR-TEM, EDXS, and FT-IR spectroscopy. The optical properties of the MPA capped ZnS:Mn nanocrystals dispersed in aqueous solution were also measured by UV/Vis and solution photoluminescence (PL) spectra, which showed a broad emission peak around 598 nm (orange light emissions) with calculated relative PL efficiency of 5.2%. Comparative toxicity evaluation of the uncoordinated ligands, MAA and MPA, with the corresponding ZnS:Mn nanocrystals revealed that the original ligands significantly suppressed the growth of wild type E. coli whereas the ligandcapped nanocrystals did not show significant toxic effects. The reduced cytotoxicity of the conjugated ZnS:Mn nanocrystals was also observed in NIH/3T3 mouse embryonic fibroblasts. These results imply that potential toxicities of the capping ligands can be neutralized on ZnS:Mn surface.
Keywords
ZnS:Mn nanocrystal; MAA and MPA capping; Toxicity; E. coli; NIH/3T3;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By Web Of Science : 1  (Related Records In Web of Science)
연도 인용수 순위
1 Dua, P.; Jeong, S.; Lee, S. E.; Hong, S. W.; Kim, S.; Lee, D.-K. Bull. Kor. Chem. Soc. 2010, 31, 1555.   DOI   ScienceOn
2 Mahto, S. K.; Park, C.; Yoon, T. H.; Rhee, S. W. Toxicol. In Vitro 2010, 24, 1070.   DOI   ScienceOn
3 Wang, L.; Zheng, H.; Long, Y.; Gao, M.; Hao, J.; Du, J.; Mao, X.; Zhou, D. J. Hazard Mater. 2010, 177, 1134.   DOI   ScienceOn
4 Zhang, Y. H.; Zhang, H. S.; Ma, M.; Guo, X. F.; Wang, H. Appl. Surf. Sci. 2009, 255, 4747.   DOI   ScienceOn
5 Alivisatos, A. P. J. Phys. Chem. 1996, 100, 13226.   DOI   ScienceOn
6 Murray, C. B.; Kagan, C. R.; Bawendi, M. G. Annu. Rev. Mater. Sci. 2000, 30, 545.   DOI   ScienceOn
7 Bhargava, R. N.; Gallagher, D.; Hong, X.; Nurmikko, A. Phys. Rev. Lett. 1994, 72, 416.   DOI   ScienceOn
8 Gan, L. M.; Liu, B.; Chew, C. H.; Xu, S. J.; Chua, S. J.; Loy, G. L.; Xu, G. Q. Langmuir 1997, 13, 6427.   DOI   ScienceOn
9 Bol, A. A.; Meijerink, A. Phys. Rev. B: Condens. Matter 1998, 58, R15997.   DOI
10 Xu, S. J.; Chua, S. J.; Liu, B.; Gan, L. M.; Chew, C. H.; Xu, G. Q. Appl. Phys. Lett. 1998, 73, 478.   DOI   ScienceOn
11 Tanaka, M.; Sawai, S.; Sengoku, M.; Kato, M.; Masumoto, Y. J. Appl. Phys. 2000, 87, 8535.   DOI   ScienceOn
12 Hwang, J. M.; Oh, M. O.; Kim, I.; Lee, J. K.; Ha, C. S. Curr. Appl. Phys. 2005, 5, 31.   DOI   ScienceOn
13 Yu, S. H.; Wu, Y. S.; Yang, J.; Han, Z.; Xie, Y.; Qian, Y.; Liu, X. Chem. Mater. 1998, 10, 2309.   DOI   ScienceOn
14 Jun, Y. W.; Jang, J. T.; Cheon, J. W. Bull. Korean Chem. Soc. 2006, 27, 961.   DOI   ScienceOn
15 Chan, W. C. W.; Nie, S. Science 1998, 281, 2016.   DOI   ScienceOn
16 Chen, C. C.; Yet, C. P.; Wang, H. N.; Chao, C. Y. Langmuir. 1999, 15, 6845.   DOI   ScienceOn
17 Yi. G.; Sun, B.; Yang, F.; Chen, D. J. Mater. Chem. 2001, 11, 2928.   DOI   ScienceOn
18 Kim, J. E.; Hwang, C. S.; Yoon, S. Bull. Kor. Chem. Soc. 2008, 29, 1247.   DOI   ScienceOn
19 Abassi, Y. A.; Jackson, J. A.; Zhu, J.; O'Connell, J.; Wang, X.; Xu, X. J. Immunol Methods 2004, 292, 195.   DOI   ScienceOn
20 Xing, J. Z.; Zhu, L.; Jackson, J. A.; Gabos, S.; Sun, X. J.; Wang, X. B.; Xu, X. Chem. Res. Toxicol. 2005, 18, 154.   DOI   ScienceOn
21 Bhargava, R. N.; Gallagher, D.; Hong, X.; Nurmikko, A. Phys. Rev. Lett. 1994, 72, 416.   DOI   ScienceOn
22 Williams, A. T. R.; Winfield, S. A.; Miller, J. N. Analyst 1983, 108, 1067.   DOI
23 Brus, L. E. Appl. Phys. A 1991, 53, 465.   DOI   ScienceOn
24 Zhuang, J.; Zhang, X.; Wang, G.; Li, D.; Yang, W.; Li, T. J. Mater. Chem. 2003, 13, 1853.   DOI   ScienceOn
25 Moszczenski, C. W.; Hooper, R. J. Inorg. Chim. Acta. 1983, 70, 71.   DOI   ScienceOn
26 Yu, W. W.; Qu, L.; Guo, W.; Peng, X. Chem. Mater. 2003, 15, 2854.   DOI   ScienceOn
27 Hardman, R. Environ. Health Perspect. 2006, 114, 165.   DOI   ScienceOn