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http://dx.doi.org/10.5012/bkcs.2012.33.2.383

Convenient One-Pot Synthesis of Sulfonamides from Thiols and Disulfides Using 1,3-Dichloro-5,5-dimethylhydantoin (DCH)  

Veisi, Hojat (Department of Chemistry, Payame Noor University)
Publication Information
Abstract
A convenient synthesis of sulfonamides from thiols and disulfides is described. In situ preparation of sulfonyl chlorides from thiols is accomplished by oxidation with 1,3-dichloro-5,5-dimethylhydantoin (DCH) under Nbenzyl-trimethylammonium chloride and water. The sulfonyl chlorides are then further allowed to react with excess amine in the same reaction vessel.
Keywords
1,3-Dichloro-5,5-dimethylhydantoin; Sulfonyl chlorides; Sulfonamides;
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