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http://dx.doi.org/10.5012/bkcs.2011.32.1.131

Synthesis of Some New Biologically Active Benzothiazole Derivatives Containing Benzimidazole and Imidazoline Moieties  

Chaudhary, Manish (Analytical & Pharmaceutical Research Laboratory, Department of Chemistry, Government College Ajmer)
Pareek, Deepak (Analytical & Pharmaceutical Research Laboratory, Department of Chemistry, Government College Ajmer)
Pareek, Pawan K. (Department of Pure and Applied Chemistry, M. D. S. University)
Kant, Ravi (Hygia Institutes of Pharmaceutical Education and Research)
Ojha, Krishan G. (Department of Pure and Applied Chemistry, M. D. S. University)
Pareek, Arun (Analytical & Pharmaceutical Research Laboratory, Department of Chemistry, Government College Ajmer)
Publication Information
Bulletin of the Korean Chemical Society / v.32, no.1, 2011 , pp. 131-136 More about this Journal
Abstract
Synthesis of N-(1H-benzimidazol-2-yl)-6-substituted-1,3-benzothiazol-2-amines and 6-substituted-N-(4,5-dihydro-1H-imidazol-2-yl)-1,3-benzothiazol-2-amines by the reaction of substituted 2-aminobenzothiazoles with carbon disulphide and methyl iodide followed by the reaction with o-phenylene diamine/ethylene diamine are reported. All the synthesized compounds were characterized by elemental analysis, IR spectra and $^1H$ NMR spectral studies. The potent antibacterial and entomological (antifeedant, acaricidal, contact toxicity and stomach toxicity) activities of the synthesized compounds were investigated.
Keywords
Benzothiazole; Benzimidazole; Imidazoline; Antibacterial activity; Entomological activity;
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