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http://dx.doi.org/10.5012/bkcs.2011.32.12.4309

Synthetic Approaches to Natural Antioxidant Benzastatin E, F and G Analogues  

Le, Thanh Nguyen (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Yang, Su-Hui (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Khadka, Daulat Bikram (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Cho, Suk-Hee (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Zhao, Chao (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Cho, Won-Jea (College of Pharmacy and Research Institute of Drug Development, Chonnam National University)
Publication Information
Bulletin of the Korean Chemical Society / v.32, no.12, 2011 , pp. 4309-4315 More about this Journal
Abstract
For synthesis of benzastatin E, F and G analogues, the indole-2-carbaldehydes with or without substituents at C-5 position were prepared as key intermediates. Several synthetic attempts to achieve benzastatin E-G analogues were suggested using the indole-2-carbaldehyde intermediates.
Keywords
Benzastatin; Antioxidant; Inhibitor of glutamate toxicity; Indole-2-carbaldehyde;
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