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http://dx.doi.org/10.5012/bkcs.2010.31.8.2299

An Expeditious Oxidative Aromatization of Hantzsch 1,4-Dihydropyridines to Pyridines Using Cetyltrimethylammonium Peroxodisulfate: A Phase Transferring Oxidant  

Kumar, Parvin (Chemistry Department, Guru Nanak Khalsa College)
Kumar, Ashwani (Drug discovery and research laboratory, Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science & Technology)
Publication Information
Bulletin of the Korean Chemical Society / v.31, no.8, 2010 , pp. 2299-2303 More about this Journal
Abstract
A new approach to the use of potassium peroxodisulphate as an oxidizing reagent is proposed and applied to the case of oxidative aromatization of 1, 4-dihydropyridines with cetyltrimethylammonium peroxodisulfate, a phase transfer oxidant. We demonstrate how it is possible to increase the reactivity of potassium peroxodisulphate in the presence of phase transfer catalyst. Dealkylation in case of 4-n-alkyl/n-alkenyl was not obtained.
Keywords
Oxidative aromatization; Cetyltrimethylammonium peroxodisulfate (CTAPDS); Phase transfer catalyst; 1,4-DHP; Cetyltrimethyl ammonium bromide;
Citations & Related Records
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Times Cited By SCOPUS : 3
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