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http://dx.doi.org/10.5012/bkcs.2010.31.7.2039

A Novel Phenylimidazo[1,2-α]pyridine Core Skeleton and Pharmacophore Model as Hypoxia-Inducible Factor Inhibitors  

Gong, Young-Dae (Innovative Drug Library Research Center, Department of Chemistry, Dongguk University)
Kang, Nam-Sook (Center for Drug Discovery Platform Technology, Korea Research Institute of Chemical Technology)
Publication Information
Bulletin of the Korean Chemical Society / v.31, no.7, 2010 , pp. 2039-2042 More about this Journal
Keywords
Phenylimidazo[1,2-$\alpha$]pyridine; Hypoxia-inducible factor (HIF); Drug-like core skeleton; Pharmacophore;
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1 Warshakoon, N. C.; Wu, S.; Boyer, A.; Kawamoto, R.; Renock, S.; Xu, K.; Pokross, M.; Evdokimov, A. G.; Zhou, S.; Winter, C.; Walter, R.; Mekel, M. Bioorg. Med. Chem. Lett. 2006, 16, 5687.   DOI
2 Ventosa-Andres, P.; Gonzalez-Vera, J. A.; Valdivielso, A. M.; Teresa Garcia-Lopez, M.; Herranz, R. Bioorg. Med. Chem. 2008, 16, 9313.   DOI
3 Sprague, P. W. Automated Chemical Hypothesis Generation and Database Searching with Catalyst. In Perspectives in Drug Discovery and Design; Muller, K., Ed.; ESCOM Science Publishers B. V.: Leiden, The Netherlands, 1995; Vol. 3, pp 1-20.
4 Leopoldo, M.; Lacivita, E.; Passafiume, E.; Contino, M.; Colabufo, N.; Berardi, F.; Perrone, Liu, R. J. Med. Chem. 2007, 50, 5043.   DOI
5 Han, Z. B.; Ren, H.; Zhao, H.; Chi, Y.; Chen, K.; Zhou, B.; Liu, Y. J.; Zhang, L.; Xu, B.; Liu, B.; Yang, R.; Han, Z. C. Carcinogenesis 2008, 29, 1853.   DOI
6 Amar, G. C.; Gundluru, M. K.; Kumar, P. B. C.; Yang, L.; Yu- Dong, Z.; Dale, G. N.; Mitchell A. A. J. Med. Chem. 2007, 50, 6299.   DOI
7 Park, J. W.; Chun, Y. S.; Kenneth, B.; Sho, H. S. WO 2005030121. 2005.
8 Jiang, B. H.; Rue, E.; Wang, R. Roe.; Semenza. G. L. J. Biol. Chem. 1996, 271, 17771.   DOI
9 Wang, G. L.; Semenza, G. L. J. Biol. Chem. 1995, 270, 1230.   DOI
10 Kaelin, W. G. Annu. Rev. Biochem. 2005, 74, 115.   DOI
11 Lee, K.; Lee, J. H.; Boovanahalil, S. K.; Jin, Y.; Lee, M.; Jin, X.; Kim, J. H.; Hong, Y.-S.; Lee, J. J. J. Med. Chem. 2007, 50, 1675.   DOI
12 Giaccia, A.; Siim, B. G.; Johnson, R. S. Nat. Rev. Drug Discovery 2003, 2, 1.   DOI
13 Choi, H. J.; Song, B.-J.; Gong, Y.-D.; Gwak, W. J.; Soh, Y. British J. Pharm. 2008, 154, 114.   DOI
14 Hwang, J. Y.; Choi, H. S.; Lee, D. H.; Gong, Y. D. J. Comb. Chem. 2005, 7, 816.   DOI
15 Hwang, J. Y.; Choi, H.-S.; Seo, J.-S.; La, H.-J.; Yoo, S.-e.; Gong, Y. D. J. Comb. Chem. 2006, 8, 897.   DOI
16 Hwang, J. Y.; Gong, Y. D. J. Comb. Chem. 2006, 8, 297.   DOI
17 Hwang, J. Y.; Choi, H. S.; Lee, D. H.; Yoo, S.-e.; Gong, Y. D. J. Comb. Chem. 2005, 7, 136.   DOI
18 Lee, I. Y.; Kim, S. Y.; Lee, J. Y.; Yu, C.-M.; Lee, D. H.; Gong, Y. D. Tetrahedron Lett. 2004, 45, 9319.   DOI
19 Concord; Tripos Inc., 1699 South Hanley Road, St. Louis, MO 63144.
20 Hert, J.; Willett, P.; Wilton, D. J.; Acklin, P.; Azzaoui, K.; Jacoby, E.; Schuffenhauer, A. J. Chem. Inf. Comp. Sci. 2004, 44, 1177.   DOI
21 Chalet, T.; Rita, G. N.; Anthony, J. R.; Beata, P.; Fatima, K.; Zhaobin, Z.; Huanchun, Z.; Quincy, T.; Ainsley, C. N.; Paraskevi, G.; Wei, Z.; Jeffrey, J. O.; Manuela, M. P.; Nicolaou, K. C.; Erwin, G. V. M. Cancer Res. 2005, 65, 605.
22 Semenza, G. L. Drug Discov. Today 2007, 12, 853.   DOI