Browse > Article
http://dx.doi.org/10.5012/bkcs.2010.31.6.1695

Protulactones A and B: Two New Polyketides from the Marine-derived Fungus Aspergillus sp. SF-5044  

Sohn, Jae-Hak (College of Medical and Life Sciences, Silla University)
Oh, Hyun-Cheol (College of Medical and Life Sciences, Silla University)
Publication Information
Bulletin of the Korean Chemical Society / v.31, no.6, 2010 , pp. 1695-1698 More about this Journal
Abstract
Protulactones A (1) and B (2), two new polyketide-derived fungal metabolites, have been isolated from an EtOAc extract of the marine-derived fungus Aspergillus sp. SF-5044 by various chromatographic methods. The structures of 1 and 2 were mainly determined by analysis of the NMR spectroscopic data and MS data, along with chemical methods such as Mosher method. Protulactones A (1) and B (2) are new members of polyketide-derived secondary metabolites, possessing unique ring systems among the fungal metabolites produced by the genus Aspergillus.
Keywords
Protulactone; Marine-derived fungus; Fungal metabolites; Polyketide; Aspergillus;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 3  (Related Records In Web of Science)
Times Cited By SCOPUS : 3
연도 인용수 순위
1 Dictionary of Natural Products on CD-ROM, Chapman & Hall/CRC Press: Boca Raton, FL, 2007.
2 Molinski, T. F.; Dalisay, D. S.; Lievens, S. L.; Saludes, J. P. Nat. Rev. Drug Discov. 2009, 8, 69.   DOI
3 Fenical, W.; Jensen, P. R. Nat. Chem. Biol. 2006, 2, 666.   DOI
4 Bugni, T. S.; Ireland, C. M. Nat. Prod. Rep. 2004, 21, 143.   DOI
5 Konig, G. M.; Kehraus, S.; Seibert, S. F.; Abdel-Lateff, A.; Muller, D. ChemBioChem 2006, 7, 229.   DOI
6 Choi, Y.-H.; Sohn, J.-H.; Lee, D.; Kim, J. K.; Kong, I. S.; Ahn, S. C.; Oh, H. Tetrahedron Lett. 2008, 49, 7128.   DOI
7 Kim, M.-Y.; Sohn, J. H.; Ahn, J. S.; Oh, H. J. Nat. Prod. 2009, 72, 2065.   DOI
8 Seo, C.; Sohn, J. H.; Oh, H.; Kim, B. Y.; Ahn, J. S. Bioorg. Med. Chem. Lett. 2009, 19, 6095.   DOI
9 Seo, C.; Oh, H. Bull. Korean Chem. Soc. 2009, 30, 1181.   DOI
10 Fang, X.P.; Anderson, J. E.; Chang, C.-J.; Fanwick, P. E.; Mc-Laughlin, J. L. J. Chem. Soc. Perkin Trans. 1 1990, 1655.
11 Takeda, Y.; Okada, Y.; Masuda, T.; Hirata, E.; Shinzato, T.; Takushi, A.; Yu, Q.; Otsuka, H. Chem. Pharm. Bull. 2000, 48, 752.   DOI
12 Seco, J. M.; Quinnoa, E.; Riguera, R. Chem. Rev. 2004, 104, 17.   DOI
13 Su, B.-N.; Park, E. J.; Mbwambo, Z. H.; Santarsiero, B. D.; Mesecar, A. D.; Fong, H. H. S.; Pezzuto, J. M.; Kinghorn, A. D. J. Nat. Prod. 2002, 65, 1278.   DOI