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http://dx.doi.org/10.5012/bkcs.2010.31.02.286

Effective Partial Alkynylation of Carboxylic Acid Derivatives to Alkynyl Ketones  

Yim, Sang-Jun (Department of Chemistry, Kangwon National University, and Institute for Molecular Science and Fusion Technology)
Kim, Min-Hyeok (Department of Chemistry, Kangwon National University, and Institute for Molecular Science and Fusion Technology)
An, Duk-Keun (Department of Chemistry, Kangwon National University, and Institute for Molecular Science and Fusion Technology)
Publication Information
Bulletin of the Korean Chemical Society / v.31, no.2, 2010 , pp. 286-290 More about this Journal
Abstract
The reaction of carboxylic acid derivatives such as esters, acid chlorides and acid anhydrides with alkynyl lithiums in the presence of lithium morpholinide and $BF_3{\cdot}OEt_2$ gave alkynyl ketones in good yield (73-96%).
Keywords
Partial alkynylation; Ynone; Ester; Acid chloride; Acid anhydride;
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