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http://dx.doi.org/10.5012/bkcs.2010.31.10.2771

Biogenic Nano-Synthesis; towards the Efficient Production of the Biocompatible Gold Nanoparticles  

Ghodake, Gajanan (Department of Life Science, College of Natural Sciences, Hanyang University)
Eom, Chi-Yong (Environment and Metabolomics Research Team, Seoul Center, Korea Basic Science Institute)
Kim, Si-Wouk (Department of Environmental Engineering, Chosun University)
Jin, Eon-Seon (Department of Life Science, College of Natural Sciences, Hanyang University)
Publication Information
Bulletin of the Korean Chemical Society / v.31, no.10, 2010 , pp. 2771-2775 More about this Journal
Abstract
We present a rapid biogenic method for the production of nanoscale gold particles using pear extract. The formation and stability of pear-derived gold nanoparticles (Pear-AuNPs) were monitored by ultraviolet-visible spectroscopy. Their morphology, elemental composition and crystalline phase were determined by transmission electron microscopy, energy-dispersive X-ray spectroscopy and selected area electron diffraction. The average core size of crystalline Pear-AuNPs was in the range of $10{\pm}5\;nm$ and the observed morphology was spherical. The X-ray photoelectron spectrum showed a strong peak for the pure 'Au' phase. The circular dichroism spectrum indicated the natural capping ability of the pear extract, which generated peptide-gold nanoparticles. These nanoparticles were stable in aqueous solution for two months. A cell viability assay of Pear-AuNPs showed biocompatibility with human embryonic kidney 293 cells. Accordingly, this eco-friendly process for the bio-mimetic production of Pear-AuNPs is nontoxic in nature; consequently, it will find potential application in nano-biotechnology.
Keywords
Biogenic; AuNPs; Cell viability assay; Nontoxic green product;
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