Browse > Article
http://dx.doi.org/10.5012/bkcs.2009.30.9.2017

Nickel Complexes of Alanine Having a Preference for One Chiral Form over Another upon Crystallization  

Khatib, Awni (Department of Chemistry, Faculty of Science and Technology, Hebron University)
Aqra, Fathi (Department of Chemistry, Faculty of Science and Technology, Hebron University)
Publication Information
Bulletin of the Korean Chemical Society / v.30, no.9, 2009 , pp. 2017-2020 More about this Journal
Abstract
Three complexes, [bis(L-, D- and DL-alaninato)(diaqua)]nickel(II) di-hydrate, were prepared and characterized by X-ray crystallography, gas chromatography, UV-Visible spectroscopy and isothermal calorimetry. Small deviations from the 50:50 distribution of the enantiomers assigned to chiral preferences of the ligands in the complexes were observed. The surprising and unexpected results indicate that complexing alanine with nickel(II) ion alters the racemization rates of D and L isomers of the amino acid. The precipitated complex due to change in pH resulted in preferential precipitation of one isomer with respect to the other. It has been observed that this alternation is ogmented by the long time span which would result in preferential protein forming from the L-isomer. Although the results are bizarre and perplexing, they are fascinating and sound scientifically.
Keywords
Racemization; Alanine complexes; Chirality;
Citations & Related Records

Times Cited By Web Of Science : 2  (Related Records In Web of Science)
Times Cited By SCOPUS : 4
연도 인용수 순위
1 Mostad, A.; Natarajan, S. Z. Kristallogr. 1987, 178, 263   DOI
2 Chatt, J.; Manojlovic-Muir, L.; Muir, K. W. Chem. Commun. 1971, 655
3 Teoh, S. G.; Chan, B. T.; Fun, H. K.; Kamwaya, M. E. Z. Kristallogr. 1987, 181, 199   DOI
4 Jianmin, L.; Cunwang, G.; Yugeng, Z. Cryst. Res. Tech. 1990, 25, K5   DOI
5 Shinitzky, M.; Shvalb, A.; Elitzur, A. C.; Mastai, Y. J. Phys. Chem. 2007, 111, 1104   DOI   ScienceOn
6 Deamer, D. W.; Dick, R.; Thiemann, W.; Shinitzky, M. Chilarity 2007, 19, 751
7 Shinitzky, M.; Deamer, D. W. Origins of Life and Evolution of Biosphere 2008, 38, 271   DOI
8 Engel, M. H.; Macko, S. A. Nature 1997, 389, 265   DOI   ScienceOn
9 Engel, M. H.; Nagy, B. Nature 1982, 296, 837   DOI
10 Engel, M. H.; Macko, S. A.; Silfer, J. A. Nature 1990, 348, 47   DOI   ScienceOn
11 Cronin, J. R.; Pizzarello, S. Science 1997, 275, 951   DOI   ScienceOn
12 Weber, A. L. Origins of Life and Evolution of the Biosphere 2008, 38, 279   DOI   ScienceOn
13 Scori, R. I.; Cimpoiasu, V. M.; Popa, R. Astrobiol. 2007, 7, 733   DOI   ScienceOn
14 Verardo, G. G.; Geatti, P.; Martinuzzi, P.; Merli, M.; Toniutti, N. Eur. J. Org. Chem. 2003, 3840
15 Khatib, A. A.; Engel, M. H. Inorg. Chim. Acta 1989, 166, 273   DOI   ScienceOn
16 Khatib, A. A., M. S. Thesis, Utah State University, Logan, UT, 1981
17 Khatib, A. A.; Aqra, F.; Deamer, D. W.; Oliver, A. Research Letters in Inorganic Chemistry 2009, 1
18 Khatib, A. A.; Aqra, F.; Deamer, D. W.; Oliver, A. South Braz. J. Chem. 2008, 16, 23
19 Smith, G. G.; Khatib, A. A.; Ready, G. S. J. Am. Chem. Soc. 1983, 105, 293   DOI
20 Khatib, A. A.; Aqra, F.; Deamer, D. W.; Oliver, A. J. Argent. Chem. Soc. 2009, 97, 1
21 Shinitzky, M.; Nudelman, F.; Barda, Y.; Haimovitz, R.; Chen, E.; Deamer, D. W. Origins of Life and Evolution of the Biosphere 2002, 32, 285   DOI   ScienceOn
22 Scolnik, Y.; Portnaya, I.; Cogan, U.; Tal, S.; Haimovitz, R.; Fridkin, M.; Elitzur, A. C.; Deamer, D. W.; Shinitzky, M. Phys. Chem. Chem. Phys. 2006, 8, 333   DOI   ScienceOn