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http://dx.doi.org/10.5012/bkcs.2009.30.9.1985

Thermal Process for Enhancing Mechanical Strength of PLGA Nanoparticle Layers on Coronary Stents  

Joo, Jae-Ryang (School of Chemistry & Molecular Engineering, Seoul National University)
Nam, Hye-Yeong (School of Chemistry & Molecular Engineering, Seoul National University)
Nam, So-Hee (School of Chemistry & Molecular Engineering, Seoul National University)
Baek, In-Su (School of Chemistry & Molecular Engineering, Seoul National University)
Park, Jong-Sang (School of Chemistry & Molecular Engineering, Seoul National University)
Publication Information
Bulletin of the Korean Chemical Society / v.30, no.9, 2009 , pp. 1985-1988 More about this Journal
Abstract
Poly (lactic-co-glycolic acid) (PLGA) nanoparticles loading paclitaxel have been deposited on coronary stents by self-assembling properties of colloidal particles. The layers of the nanoparticles were enhanced to a sufficient mechanical strength by a thermal process under the proper temperature and humidity conditions. In vitro release studies proved the controlled paclitaxel release of the nanoparticle layers. This technique gives rise to a new range of applications for nanoparticles and drug-eluting stents.
Keywords
Stent; Paclitaxel; PLGA; Nanoparticle; Thermal process;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
Times Cited By Web Of Science : 2  (Related Records In Web of Science)
Times Cited By SCOPUS : 2
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1 Brannon-Peppas, L. Int. J. Pharm. 1995, 116, 1   DOI   ScienceOn
2 Jain, R. A. Biomaterials 2000, 21, 2475   DOI   ScienceOn
3 Yamaguchi, Y.; Takenaga, M.; Kitagawa, A.; Ogawa, Y.; Mizushima, Y.; Igarashi, R. J. Control. Release 2002, 81, 235   DOI   ScienceOn
4 Nam, S. H.; Nam, H. Y.; Joo, J. R.; Baek, I. S.; Park, J. Bull. Korean Chem. Soc. 2007, 28, 397   DOI   ScienceOn
5 Panyam, J.; Labhasetwar, V. Adv. Drug Deliv. Rev. 2003, 55, 329   DOI   ScienceOn
6 Florence, A. T. Pharm. Res. 1997, 14, 259   DOI   ScienceOn
7 Aprahamian, M.; Michel, C.; Humbert, W.; Devissaguet, J. P.; Damge, C. Biol. Cell 1987, 61, 69   DOI
8 Oppenheim, R. C.; Stewert, N. F.; Gordon, L.; Patel, H. M. Drug Dev. Ind. Pharm. 1982, 8, 531   DOI
9 Westedt, U.; Kalinowski, M.; Wittmar, M.; Merdan, T.; Unger, F.; Fuchs, J.; Schaller, S.; Bakowsky, U.; Kissel, T. J. Control. Release 2007, 119, 41   DOI   ScienceOn
10 Kushwaha, V.; Bhowmick, A.; Behera, B. K.; Ray, A. R. Artif. Cells, Blood Substit. & Immobil. Biotechnol. 1998, 26, 159   DOI
11 Joo, J.; Nam, H. Y.; Nam, S. H.; Baek, I.; Park, J. Bull. Korean Chem. Soc. 2009, 30, 1085   DOI   ScienceOn
12 Prevo, B. G.; Velev, O. D. Langmuir 2004, 20, 2099   DOI   ScienceOn
13 Feng, S. S.; Huang, G. J. Control. Release 2001, 71, 53   DOI   ScienceOn
14 Sousa, J. E.; Costa, M. A.; Abizaid, A. C.; Rensing, B. J.; Abizaid, A. S.; Tanajura, L. F.; Kozuma, K.; van Langenhove, G.; Sousa, A. G. M. R.; Falotico, R.; Jaeger, J.; Popma, J. J.; Serruys, P. W. Circulation 2001, 104, 2007   DOI   ScienceOn
15 Bertrand, O. F.; Sipehia, R.; Mongrain, R.; Rodés, J.; Tardif, J.; Bilodeau, L.; Cote, G.; Bourassa, M. G. J. Am. Coll. Cardiol. 1998, 32, 562   DOI   ScienceOn
16 Moses, J. W.; Kipshidze, N.; Leon, M. B. Am. J. Cardiovasc. Drugs 2002, 2, 163   DOI   ScienceOn
17 Kornowski, R.; Hong, M. K.; Tio, F. O.; Bramwell, O.; Wu, H.; Leon, M. B. J. Am. Coll. Cardiol. 1998, 31, 224   DOI   ScienceOn
18 Duda, S. H.; Poerner, T. C.; Wiesinger, B.; Rundback, J. H.; Tepe, G.; Wiskirchen, J.; Haase, K. K. J. Vasc. Interv. Radiol. 2003, 14, 291   DOI   ScienceOn
19 Woods, T. C.; Marks, A. R. Annu. Rev. Med. 2004, 55, 169   DOI   ScienceOn
20 Huizing, M. T.; Misser, V. H.; Pieters, R. C.; ten Bokkel Huinink, W. W.; Veenhof, C. H.; Vermorken, J. B.; Pinedo, H. M.; Beijnen, J. H. Cancer Invest. 1995, 13, 381   DOI   ScienceOn
21 Nam, H. Y.; Kim, D. J.; Lim, H. J.; Lee, B. H.; Baek, I. S.; Park, J. S. Bull. Korean Chem. Soc. 2008, 29, 422   DOI   ScienceOn
22 Rowinsky, E. K.; Donehower, R. C. N. Engl. J. Med. 1995, 332, 1004   DOI   ScienceOn
23 Farb, A.; Heller, P. F.; Shroff, S.; Cheng, L.; Kolodgie, F. D.; Carter, A. J.; Scott, D. S.; Froehlich, J.; Virmani, R. Circulation 2001, 104, 473   DOI   ScienceOn
24 Drachman, D. E.; Edelman, E. R.; Seifert, P.; Groothuis, A. R.; Bornstein, D. A.; Kamath, K. R.; Palasis, M.; Yang, D.; Nott, S. H.; Rogers, C. J. Am. Coll. Cardiol. 2000, 36, 2325   DOI   ScienceOn
25 Fischman, D. L.; Leon, M. B.; Baim, D. S.; Schatz, R. A.; Savage, M. P.; Penn, I.; Detre, K.; Veltri, L.; Ricci, D.; Nobuyoshi, M.; Cleman, M.; Heuser, R.; Almond, D.; Teirstein, P. S.; Fish, R. D.; Colombo, A.; Brinker, J.; Moses, J.; Shaknovich, A.; Hirshfeld, J.; Bailey, S.; Ellis, S.; Rake, R.; Goldberg, S.; for The Stent Restenosis Study Investigators. N. Engl. J. Med. 1994, 331, 496   DOI   ScienceOn
26 Unger, F. Cor. Europaeum 1999, 7, 128
27 Gruntzig, A. R.; Senning, A; Siegenthaler, W. E. N. Engl. J. Med. 1979, 301, 61   DOI   ScienceOn
28 Serruys, P. W.; de Jaegere, P.; Kiemeneij, F.; Macaya, C.; Rutsch, W.; Heyndrickx, G.; Emanuelsson, H.; Marco, J.; Legrand, V.; Materne, P.; Belardi, J.; Sigwart, U.; Colombo, A.; Goy, J. J.; van den Heuvel, P.; Delcan, J.; Morel, M,; for the Benestent Study Group. N. Engl. J. Med. 1994, 331, 489   DOI   ScienceOn
29 van der Hoeven, B. L.; Pires, N. M. M.; Warda, H. M.; Oemrawsingh, P. V.; van Vlijmen, B. J. M.; Quax, P. H. A.; Schalij, M. J.; van der Wall, E. E.; Jukema, J. W. Int. J. Cardiol. 2005, 99, 9   DOI   ScienceOn
30 Sousa, J. E. ; Serruys, P. W.; Costa, M. A. Circulation 2003, 107, 2274   DOI   ScienceOn
31 Grube, E.; Silber, S.; Hauptmann, K. E.; Mueller, R.; Buellesfeld, L.; Gerckens, U.; Russell, M. E. Circulation 2003, 107, 38   DOI   ScienceOn
32 Regar, E.; Serruys, P. W.; Bode, C.; Holubarsch, C.; Guermonprez, J. L.; Wijns, W.; Bartorelli, A.; Constantini, C.; Degertekin, M.; Tanabe, K.; Disco, C.; Wuelfert, E.; Morice, M. C.; on behalf of the RAVEL Study Group. Circulation 2002, 106, 1949   DOI   ScienceOn