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http://dx.doi.org/10.5012/bkcs.2009.30.11.2555

Ammonium Acetate: An Efficient Reagent for the One-pot Synthesis of 5-Aryl-7,8,13,14-tetrahydrodibenzo[a,i] phenanthridines, 2,4-Diaryl-6,7-benzo-3-azabicyclo[3.3.1]nonan-9-ones and α,α'-Bis(substituted benzylidene)cycloalkanones  

Karthikeyan, Natesan Sundaramurthy (Chemistry Division, School of Science and Humanities, VIT University)
Sathiyanarayanan, Kulathu Iyer (Chemistry Division, School of Science and Humanities, VIT University)
Aravindan, Paduthapillai Gopal (Physics Division, School of Science and Humanities, VIT University)
Publication Information
Bulletin of the Korean Chemical Society / v.30, no.11, 2009 , pp. 2555-2558 More about this Journal
Abstract
The condensation of cyclic ketone with aromatic aldehydes in the presence of ammonium acetate under ethanol media affords the corresponding 5-aryl-7,8,13,14-tetrahydrodibenzo[a,i]phenanthridine with excellent yield. This mild and efficient procedure with high yield is also applied to the synthesis of 2,4-diaryl-6,7-benzo-3-azabicyclo- [3.3.1]nonan-9-ones and ${\alpha},{\alpha}{$’-bis(substituted benzylidene)cycloalkanones.
Keywords
Cyclic ketone; Aromatic aldehyde; Ammonium acetate; Mannich reaction; Cross aldol condensation;
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