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http://dx.doi.org/10.5012/bkcs.2008.29.10.1998

Approaches to the Syntheses of Partially Reduced Imidazo[1,2-a]pyridines  

Shin, Jun-Hwa (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
Nho, Young-Chang (Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute)
Howard, Arthur S. (Department of Chemistry, Eastern Michigan University)
Publication Information
Bulletin of the Korean Chemical Society / v.29, no.10, 2008 , pp. 1998-2004 More about this Journal
Abstract
Two synthetic pathways to substituted hexahydroimidazo[1,2-a]pyridines, which may serve as precursors of aza-alkaloids, were investigated. The first involves the condensation of a bisnucleophilic enediaminoester and a biselectrophile. The second involves attachment to nitrogen of the carbon chain skeleton required to form the six-memberd ring, before formation of the enediaminoester. Several substituted hexahydroimidazo[1,2- a]pyridines were synthesized via these two approaches.
Keywords
Aza-alkaloid; Heterocyclic compounds; Indolizidine
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Times Cited By Web Of Science : 0  (Related Records In Web of Science)
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