Browse > Article
http://dx.doi.org/10.5012/bkcs.2007.28.9.1573

Fluorescence Quenching of Norfloxacin by Divalent Transition Metal Cations  

Park, Hyoung-Ryun (Department of Chemistry and Nano Technology Research Center, Chonnam National University)
Seo, Jung-Ja (Department of Chemistry and Nano Technology Research Center, Chonnam National University)
Shin, Sung-Chul (Department of Chemistry and Research Institute of Life Science, Gyeongsang National University)
Lee, Hyeong-Su (Department of Chemical Education and Research Institute of Life Science, Gyeongsang National University)
Bark, Ki-Min (Department of Chemical Education and Research Institute of Life Science, Gyeongsang National University)
Publication Information
Bulletin of the Korean Chemical Society / v.28, no.9, 2007 , pp. 1573-1578 More about this Journal
Abstract
Fluorescence quenching of norfloxacin (NOR) by Cu2+, Ni2+, Co2+ and Mn2+ was studied in water. The change in the fluorescence intensity and lifetime was measured as a function of quencher concentration at various temperatures. According to the Stern-Volmer plots, the NOR was quenched both by collisions and complex formation with the same quencher. However, the static quenching had a more important effect on the emission. Large static and dynamic quenching constants support significant ion-dipole and orbital-orbital interactions between NOR and cations. The both quenching constants by Cu2+ were the largest among quenchers. Also, quenching mechanism of Cu2+ was somewhat different. The change in the absorption spectra due to the quencher provided information on static quenching. The fluorescence of NOR was relatively insensitive to both the dynamic and static quenching compared with other quinolone antibiotics. This property can be explained by the twisted intramolecular charge transfer.
Keywords
Fluorescence quenching; Norfloxacin; Transition metal cation; Stern-Volmer plot; Intramolecular charge transfer;
Citations & Related Records
Times Cited By KSCI : 1  (Citation Analysis)
Times Cited By Web Of Science : 10  (Related Records In Web of Science)
Times Cited By SCOPUS : 10
연도 인용수 순위
1 Appelbaum, P. C.; Hunter, P. A. Int. J. Antimicrob. Agent 2000, 16, 5   DOI   ScienceOn
2 Mizuki, Y.; Fujiwara, I.; Yamaguchi, T. J. Antimicrob. Chemother. 1996, 37(Suppl. A), 41   DOI   ScienceOn
3 Ball, P. J. Antimicrob. Chemother. 2000, 46(Topic T1), 17   DOI   ScienceOn
4 Koga, H.; Itoh, A.; Murayama, S.; Suzue, S.; Irikura, T. J. Med. Chem. 1980, 23, 1358   DOI
5 Sanz-Nebot, V.; Valls, I.; Barbero, D.; Barbosa, J. Acta Chemica Scandinavica 1997, 51, 896
6 Andriole, V. T.; Smith, J. T.; Lewin, C. S. The Quinolones; Academic press: New York, U.S.A., 1988; p 23
7 Park, H. R.; Oh, C. H.; Lee, H. C.; Lee, J. K.; Yang, K.; Bark, K. M. Photochem. Photobiol. 2002, 75, 237   DOI   ScienceOn
8 Rettig, W. J. Mol. Structure 1982, 84, 303   DOI   ScienceOn
9 Park, H. R.; Chung, K. Y.; Lee, H. C.; Lee, J. K.; Bark, K. M. Bull. Korean Chem. Soc. 2000, 21, 849
10 Slater, J.; Mildvan, A.; Loeb, L. Biochem. Biophys. Res. Commun. 1971, 44, 37   DOI   ScienceOn
11 Springgate, C.; Mildvan, A.; Abramson, R.; Engle, J.; Loeb, L. J. Biol. Chem. 1973, 248, 5987
12 Valenzuela, P.; Morris, R.; Faras, A.; Levinson, W.; Rutter, W. Biochem. Biophys. Res. Commun. 1973, 53, 1036   DOI   ScienceOn
13 Park, H. R.; Oh, C. H.; Lee, H. C.; Choi, J. G.; Jung, B. I.; Bark, K. M. Bull. Korean Chem. Soc. 2006, 27, 2002   DOI   ScienceOn
14 Gonzalez-Jimmenez, J.; Frutos, G.; Cayre, I. Biochem. Pharmacol. 1992, 44, 824
15 Thulborn, K. R.; Sawyer, W. H. Biochim. Biophys. Acta 1978, 511, 125   DOI   ScienceOn
16 Seidel, C. A. M.; Schulz, A.; Sauer, M. H. M. J. Phys. Chem. 1996, 100, 5541   DOI   ScienceOn
17 Kubota, Y.; Motoda, Y.; Shigemune, Y.; Fujisaki, Y. Photochem. Photobiol. 1979, 29, 1099   DOI
18 Posokhov, Y.; Kus, M.; Biner, H.; Gumus, M. K.; Tugcu, F. T.; Aydemir, E.; Kaban, S.; Icli, S. J. Photochem. Photobiol. 2004, 161, 247   DOI   ScienceOn
19 Fabbrizzi, L.; Licchelli, M.; Pallavicini, P. Acc. Chem. Res. 1999, 32, 846   DOI   ScienceOn
20 Martinez, L.; Bilski, P.; Chignell, C. F. Photochem. Photobiol. 1996, 64, 911   DOI   ScienceOn
21 Park, H. R.; Lee, H. C.; Kim, T. H.; Lee, J. K.; Yang, K.; Bark, K. M. Photochem. Photobiol. 2000, 71, 281   DOI   ScienceOn
22 Kang, J. S.; Kim, T. H.; Park, K. B.; Chung, B. H.; Youn, J. I. Photodermatol. Photoimmunol. Photomed. 1993, 9, 159
23 Sun, Y. W.; Heo, E. P.; Cho, Y. H.; Bark, K. M.; Yoon, T. J.; Kim, T. H. Photodermatol. Photoimmunol. Photomed. 2001, 17, 172   DOI   ScienceOn
24 Ferguson, J. Photochem. Photobiol. 1995, 62, 954   DOI
25 Park, H. R.; Oh, C. H.; Lee, H. C.; Lim, S. R.; Yang, K.; Bark, K. M. Photochem. Photobiol. 2004, 80, 554   DOI
26 Demas, J. N.; Grosby, G. A. J. Phys. Chem. 1971, 75, 2463   DOI
27 Lakowicz, J. R. Principles of fluorescence spectroscopy, 2nd ed.; Kluwer Academic/Plenum Publishers: New York, U.S.A., 1999
28 Eaton, D. F. Reference compounds for fluorescence measurement; IUPAC Organic Chem. Division: Wilmington, U.S.A., 1987; p 1
29 Bark, K. M.; Force, R. K. Spectrochim. Acta 1993, 49(A), 1605   DOI   ScienceOn
30 Zhang, J.; Bright, F. V. J. Phys. Chem. 1991, 95, 7900   DOI
31 Lakowicz, J. R.; Lackzo, G.; Gryczynski, I.; Szmacinski, H.; Wiczk, W. J. Photochem. Photobiol. B Biol. 1988, 2, 295   DOI   ScienceOn
32 Jameson, D. M.; Gratton, E.; Hall, R. D. Appl. Spectrosc. Rev. 1984, 20, 105
33 Kessler, M. A. Anal. Chim. Acta 1998, 364, 125   DOI   ScienceOn
34 Drevensek, P.; Turel, I.; Ulrih, N. P. J. Inorg. Biochem. 2003, 96, 407   DOI   ScienceOn
35 Fabbrizzi, L.; Poggi, A. Chem. Soc. Rev. 1995, 24, 197   DOI   ScienceOn