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http://dx.doi.org/10.5012/bkcs.2007.28.2.229

A New Chemical Constituent from the Hairy Root Cultures of Catharanthus roseus  

Chung, Ill-Min (Department of Applied Life Science, Konkuk University)
Park, Han-Young (Department of Applied Life Science, Konkuk University)
Ali, Mohd (Faculty of Pharmacy, Hamdard University)
San, Ka Yiu (Department of Bioengineering, Rice University)
Peebles, Christie A. M. (Department of Bioengineering, Rice University)
Hong, Seung-Beom (Department of Applied Life Science, Konkuk University)
Ahmad, Ateeque (Department of Applied Life Science, Konkuk University)
Publication Information
Bulletin of the Korean Chemical Society / v.28, no.2, 2007 , pp. 229-234 More about this Journal
Abstract
One new compound, 3,7,11,19,23,27-hexamethyl-15-hydroxymethylene-n-octacos-5,8,20-triene-10β,18α- diol-10β-D-glucopyranoside (1), along with the three known compounds, 3-epibetulinic acid (2), n-pentadecanyl octa-dec-19-en-oate (3) and β-sitosterol (4) were isolated from the methanolic extract of the cultured Catharanthus roseus hairy roots. The structures of the one new and three known compounds were elucidated using one- and two-dimensional NMR in combination with IR, EI/MS, FAB/MS. To the best of our knowledge, 3,7,11,19,23,27-hexamethyl-15-hydroxymethylene-n-octacos-5,8,20-triene-10β,18α-diol-10β-D-glucopyranoside, 3-epibetulinic acid and n-pentadecanyl octa-dec-19-en-oate were identified for the first time from the hairy roots of C. roseus.
Keywords
Catharanthus roseus; Apocynaceae; Culture hairy root composition; New and known compounds;
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Times Cited By Web Of Science : 8  (Related Records In Web of Science)
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