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http://dx.doi.org/10.5012/bkcs.2007.28.11.1931

Synthesis and Properties of Soluble and Stable Silyl End-capped Bis-thienylanthracene Oligomers  

Choi, Jung-Hei (Department of Chemistry and the Center for Plastic Information System, Pusan National University)
Cho, Dae-Won (Department of Chemistry and the Center for Plastic Information System, Pusan National University)
Sung, Nam-Kyoung (Department of Chemistry and the Center for Plastic Information System, Pusan National University)
Jin, Sung-Ho (Department of Chemistry Education and the Center for Plastic Information System, Pusan National University)
Yoon, Ung-Chan (Department of Chemistry and the Center for Plastic Information System, Pusan National University)
Publication Information
Bulletin of the Korean Chemical Society / v.28, no.11, 2007 , pp. 1931-1938 More about this Journal
Abstract
Analyzed are recent advances in design of novel boronared conjugates of synthetic and natural porphyrins and chlorins. These compounds showed high efficacy as cytotoxic agents for tumor cells in culture and as phototoxins in photodynamic therapy of tumor xenografts. Thus, boronated porphyrins and chlorins emerge as promising class of anticancer agents with potentially multiple advantages: the chemotherapeutic drugs alone and photo- and radiosensitizers in binary treatments.
Keywords
Thiophene oligomer; Bis-oligothienylanthracene; Silyl end-capping group; Stille reaction;
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