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http://dx.doi.org/10.5012/bkcs.2007.28.10.1739

An Efficient and Concise Synthesis of Biologically Interesting Pyranochromenes by Ethylenediamine Diacetate-Catalyzed Double Condensation of Substituted Trihydroxybenzenes to α,β-Unsaturated Aldehydes and Application to Natural Product Analoges  

Lee, Yong-Rok (School of Chemical Engineering and Technology, Yeungnam University)
Li, Xin (School of Chemical Engineering and Technology, Yeungnam University)
Publication Information
Bulletin of the Korean Chemical Society / v.28, no.10, 2007 , pp. 1739-1745 More about this Journal
Abstract
A new methodology for the preparation of pyranochromenes was developed starting from substituted trihydroxybenzenes. This methodology was applied successfully to the total synthesis of biologically interesting compounds, clusiaphenone A, octandrenolone, O-methyloctandrenolone, trans-3''',4'''-dihydro- 3''',4'''-dihydroxy-O-methyloctandrenolone, trans-3'',4''-dihydro-3'',4''-dihydroxy-O-methyloctandrenolone, flemiculosin, laxichalcone, and racemic 3-deoxy-Ms-II.
Keywords
Pyranochromene; Double condensation; Trihydroxybenzenes; Electrocyclization;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 6  (Related Records In Web of Science)
Times Cited By SCOPUS : 0
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