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http://dx.doi.org/10.5012/bkcs.2006.27.9.1289

Structure and Biological Activity of K(H2O)L (L = 5,7-Dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate)  

Guo, Ya-Ning (School of Chemistry and Materials Science, Shaanxi Normal University)
Zhang, Xue-Ling (School of Chemistry and Materials Science, Shaanxi Normal University)
Zhang, Zun-Ting (School of Chemistry and Materials Science, Shaanxi Normal University)
Publication Information
Bulletin of the Korean Chemical Society / v.27, no.9, 2006 , pp. 1289-1292 More about this Journal
Abstract
Potassium(I) with 5,7-dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate (L) assembles to K($H_2O$)L (L = 5,7-dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate). It was characterized by single-crystal X-ray diffraction, element analysis, IR and $^1H$ NMR spectroscopy. It crystallizes in the monoclinic space group $P2_1$/n and reveals a seven-coordinate complex. Polyhedra potassium chains, C-H${\cdot}{\cdot}{\cdot}\pi$ and C-H${\cdot}{\cdot}{\cdot}$O and O-H${\cdot}{\cdot}{\cdot}$O hydrogen bonds lead K($H_2O$)L to a three-dimensional network structure. The biological activity of resistance to hypoxia was tested, and the results showed that the biological activity of resistance to hypoxia of K($H_2O$)L is as good as that of its precursor, irisolidone.
Keywords
5,7-Dihydroxy-6,4'-dimethoxyisoflavone-3'-sulfonate; Irisolidone; Crystal structure; Biological activity;
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