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http://dx.doi.org/10.5012/bkcs.2002.23.9.1285

A Facile One-Pot Operations of Reduction and Allylation of Nitrobenzaldehydes Mediated by Indium and Their Applications  

Cho, Yong-Seo
Kang, Kyung-Ho
Cha, Joo-Hwan
Choi, Kyung-Il
Pae, Ae-Nim
Koh, Hun-Yeong
Chang, Moon-Ho
Publication Information
Bulletin of the Korean Chemical Society / v.23, no.9, 2002 , pp. 1285-1290 More about this Journal
Abstract
Various nitrobenzaldehydes were simultaneously allylated and reduced using indium in the presence of HCl in aqueous media to give compounds having both functionality of homoallylic alcohol and aromatic amine. Sequential protection of the amino gro up and oxidation of the anilinyl homoallylic alcohol provided useful precursors of heterocyclic compounds such as dihydroindolones and dihydroquinolones, which could be efficiently synthesized through intramolecular cyclization reaction.
Keywords
Simultaneous reduction-allylation; Indium; Aqueous media;
Citations & Related Records

Times Cited By Web Of Science : 7  (Related Records In Web of Science)
Times Cited By SCOPUS : 9
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