1 |
Isatin derivative 1a-d were prepared from isatin as follows
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N-acetylisatin
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2 |
with benzoic anhydride (CH2CL2,Et3N, rt, 3 h, 80%)
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N-tosylisatin
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3 |
with acetic anhydride (80-90 C, 3h, 79%)
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N-propionylisatin
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4 |
with p-toluenesulfony1 chloride (CH2Cl2, Et3N, rt, 3 h, 50%)
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5 |
with propionyl chloride(CH2Cl2, pyridine, rt, 2 h, 94%)
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N-benzoylisatin
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6 |
Yoshioka, M.; Yoshida, A.; Ichihashi, Y.; Saito, H. Chem. Pharm. Bull. 1985, 33, 2145.
DOI
ScienceOn
|
7 |
Gathergood, N.; Zhuang, W.; Jorgensen, K. A. J. Am. Chem. Soc. 2000, 122, 12517.
DOI
ScienceOn
|
8 |
Soai, K.; Hasegawa, H. J. Chem. Soc., Perkin Trans. 1 1985, 769.
|
9 |
Meyer, F. J. Chem. Ber. 1966, 99, 3060.
DOI
|
10 |
Nishihata, T.; Takahagi, H.; Yamamoto, M.; Tomida, H.; Rytting, J. H.; Higuchi, T. J. Pharm. Sci. 1984, 73, 109.
DOI
|
11 |
Solodin, I.; Goldberg, Y.; Zelcans, G.; Lukevics, E. J. Chem. Soc., Chem. Commun. 1990, 1321.
|
12 |
Byun, I. S.; Kim, Y. H. Synth. Commun. 1995, 25, 1963.
DOI
ScienceOn
|
13 |
Xiang, Y. B.; Snow, K.; Belley, M. J. Org. Chem. 1993, 58, 993.
DOI
|
14 |
Popp, F. D.; Piccirilli, R. M. J. Heterocyclic Chem. 1971, 8, 473.
DOI
|
15 |
Russell, A. E.; Miller, S. P.; Morken, J. P. J. Org. Chem. 2000, 65, 8381.
DOI
ScienceOn
|
16 |
Kiegiel, K.; Jurczak, J. Tetrahedron Lett. 1999, 40, 1009.
DOI
ScienceOn
|
17 |
de Mayo, P.; Ryan, J. J. Can. J. Chem. 1967, 45, 2117.
DOI
|
18 |
Angell, E. C.; Black, D. St C.; Kumar, N. Magn. Reson. Chem. 1992, 30, 1.
|
19 |
Dayan, S.; Bareket, Y.; Rozen, S. Tetrahedron 1999, 55, 3657.
DOI
ScienceOn
|
20 |
El-Nimr, A. E.; Salama, H. A.; Khalil, R. M.; Kassem, M. A. Pharmazie 1983, 38, 728.
|
21 |
Hoover, J. R. E.; Dunn, G. L.; Jakas, D. R.; Lam, L. L.; Taggart, J. J.; Guarini, J. R.; Phillips, L. J. Med. Chem. 1974, 17, 34.
DOI
|
22 |
Soai, K.; Isoda, T.; Hasegawa, H.; Ishizaki, M. Chem. Lett. 1986, 1897.
|
23 |
Franke, A. Liebigs Ann. Chem. 1982, 794.
|
24 |
Khalaj, A.; Shadnia, H.; Sharifzadeh, M. Pharm. Pharmacol. Commun. 1998, 4, 373.
|
25 |
Bergman, J.; Carlsson, R.; Lindstrom, J.-O. Tetrahedron Lett. 1976, 3611.
|
26 |
Soai, K.; Komiya, K.; Shigematsu, Y.; Hasegawa, H.; Ookawa, A. J. Chem. Soc., Chem. Commun. 1982, 1282.
|
27 |
Soai, K.; Ishizaki, M. J. Org. Chem. 1986, 51, 3290.
DOI
|
28 |
Soai, K.; Ishizaki, M. J. Chem. Soc., Chem. Commun. 1984, 1016.
|
29 |
Miersch, O.; Kramell, R.; Parthier, B.; Wasternack, C. Phytochemistry 1999, 50, 353.
DOI
ScienceOn
|
30 |
Kiegiel, J.; Papis, A.; Jurczak, J. Tetrahedron: Asymmetry 1999, 10, 535.
DOI
ScienceOn
|