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http://dx.doi.org/10.5369/JSST.2015.24.6.423

Characteristics of Gold and Silver Bimetallic Surface Plasmon Resonance Chip in Intensity Measurement Mode and Calculation of Refractive Index using Critical Angle  

Kim, Hyungjin (Dept. of Biomedical Engineering, Catholic University of Daegu)
Lee, Sung-Youp (Dept. of Physics, Kyungpook National Unversity)
Kim, Hong Tak (Dept. of Physics, Kyungpook National Unversity)
Yang, Ki-Won (Dept. of Physics, Kyungpook National Unversity)
Sohn, Young-Soo (Dept. of Biomedical Engineering, Catholic University of Daegu)
Publication Information
Journal of Sensor Science and Technology / v.24, no.6, 2015 , pp. 423-428 More about this Journal
Abstract
A bimetallic chip made of gold and silver was investigated in intensity interrogation mode to confirm enhancement of the SPR sensor resolution. Both reflectance curves of the bimetallic chip and the conventional gold chip was acquired and compared. The line width of the reflectance curve of the bimetallic chip was narrower than that of the conventional Au chip, resulting in steeper tangential slope. The reflectance was monitored at the angle related to the steepest tangential slope. The change in reflectance of the bimetallic chip was larger than that of the Au chip. The critical angle was analyzed by differentiating the reflectance with respect to incident angle twice. Acquiring the critical angle regarding to the sample informs the refractive index of the sample. Using various concentration of Bovine Serum Albumin, we confirmed that refractive index was linearly related to variation of reflectance of the bimetallic chip.
Keywords
Bimetallic chip; SPR sensor; Intensity interrogation mode; Critical angle; Refractive index;
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1 Y. S. Shin, J. H. Yoon, and D. G. Hwang, "Establishing a new paradigm for healthcare", Korea institute for Health and social affairs. 2012.
2 S. K. Kim, D. H. Ahn, H. J. Kim, and G. S. Sin, "How to Make Healthcare Industry More Competitive Through Innovation", Science and technology policy institute, 2012.
3 http://crpc.kist.re.kr/kor/_03info/brief_view.jsp?bkey=1437 (retrieved on Aug. 20, 2015).
4 P. J. Conroy, S. Hearty, P. Leonard, and R. J. O'Kennedy, "Antibody production, design and use for biosensor based applications", Semin. Cell Dev. Biol., Vol. 20, pp. 10-26, 2009.   DOI
5 R. M. Lequin, "Enzyme Immunoassay(EIA)/Enzyme Linked Immunosorbent Assay", Clin. Chem., Vol. 51, pp. 2415-2418, 2005.   DOI
6 S. K. Vashist, E. M. Schneider, and J. H. T. Luong, " Rapid psandwich ELISA-based in vitro diagnostic procedure for the highly-sensitive detection of human fetuin A", Biosensors and Bioelectronics, Vol. 67, pp. 73-78, 2015.   DOI
7 S. H. Choi, Y. M. Yang, and J. S. Chae, " Surface plasmon resonance protein sensor using Vroman effect", Biosensors and Bioelectronics, Vol. 24, pp. 893-899, 2008.   DOI
8 H. Sipova, and J. Homola, "Surface plasmon resonance sensing of nucleic acids: A review", Analytica Chimica Acta, Vol. 773, pp. 9-23, 2013.   DOI
9 C. Bian, J. Tong, J. Sun, and H. Zhang, Q. Xue, S. Xia, "A field effect transistor(FET)-based immunosensor for detection of HbA1c and Hb", Biomed. Microdevices, Vol.13, No. 2, pp. 345-352, 2011.   DOI
10 Y. Liu, L. M. Schweizer, W. Wang, R. Reuben, M. Schweizer, and W. Shu, "Label-free and real-time monitoring of yeast cell growth by the bending of polymer microcantilever biosensors", Sensors and Actuators B. Vol. 178, pp. 621-626, 2013.   DOI
11 Y. K. Lee, Y. -S. Sohn, K. -S. Lee, W. M. Kim, and J. -O. Lim, "Waveguide-coupled bimetallic film for enhancing the sensitivity of a surface plasmon resonance sensor in a fixedangle mode", Journal of the Korean Physical Society, Vol. 62, No. 3, pp. 475-480, 2013.   DOI
12 Y. K. Lee, K. -S. Lee, W. M. Kim, and Y. -S. Sohn, "Detection of amyloid-${\beta}42$ using a waveguide coupled bimetallic surface plasmon resonance sensor chip in the intensity measurement mode", PLoS ONE, Vol. 9, Issue 6, e98992, 2014.   DOI
13 B. H. Ong, X. Yuan, S. C. Tjin, J. Zhang, and H. M. Ng, "Optimised film thickness for maximum evanescent field enhancement of a bimetallic film surface plasmon resonance biosensor", Sensors and Actuators B, Vol. 114, pp. 1028-1034, 2006.   DOI
14 A. K. Sharma, and B. D. Gupta, "On the performance of different bimetallic combinations in surface plasmon resonance based fiber optic sensors", Journal of applied physics, Vol. 7, 093111, 2007.
15 S. A. Zynio, A. V. Samoylov, E. R. Surovtseva, V. M. Mirsky, and Y. M. Shirshov, "Bimetallic layers increase sensitivity of affinity sensors basedon surface plasmon resonance", Sensors, Vol. 2, pp. 62-70, 2002.
16 J. Homola, S. S. Yee, and G. Gauglitz, "Surface plasmon resonance sensors: review", Sensors and Actuators B, Vol. 54, pp. 3-15, 1999.   DOI
17 L. Xia, S. Yin, H. Gao, Q. Deng, and C. Du, "Sensitivity enhancement for surface plasmon resonance imaging biosensor by utilizing gold-silver bimetallic film configuration", Plasmonics, Vol. 6, pp. 245-250, 2011.   DOI
18 F. -C. Chien, and S. -J. Chen, "A sensitivity comparison of optical biosensors based on four different surface plasmon resonance modes", Biosensors and Bioelectronics, Vol. 20, pp. 633-642, 2004.   DOI