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http://dx.doi.org/10.5369/JSST.2013.22.3.219

Analysis of COPD Patient's Exhaled Breath Using Sensor Array  

Yu, Joon-Boo (Bio-Medical Research Institute, Kyungpook National Unversity)
Lee, Shin-Yup (Department of Internal Medicine, School of Medicine, Kyungpook National University)
Jeon, Jin-Young (Department of Electronic, Information & Communication Engineering, Kangwon National University)
Byun, Hyung-Gi (Department of Electronic, Information & Communication Engineering, Kangwon National University)
Lim, Jeong-Ok (Bio-Medical Research Institute, Kyungpook National Unversity)
Publication Information
Journal of Sensor Science and Technology / v.22, no.3, 2013 , pp. 219-222 More about this Journal
Abstract
The exhaled breath contains gases generated from human body. When disease occurs in the body, exhaled breath may include gas components released from disease metabolism. If we can find specific elements through analysis of the exhaled gases, this approach is an effective way to diagnose the disease. The lung function has a close relationship with exhalation. Exhaled gases from COPD (Chronic Obstructive Pulmonary Disease) patients can be analyzed by gas chromatography-mass spectroscopy (GC-MS) and a gas sensor system. The exhaled breath for healthy person and COPD patients had different components. Significantly more benzendicarboxylic acid was detected from COPD patients than in healthy persons. In addition, patients had a variety of decane. Phosphorous compounds with different isomers were detected from patients. The results obtained by gas sensor system were processed by PCA (Principal Component Analysis). The PCA results revealed distinct difference between the patients and healthy people.
Keywords
GC-MS; COPD; Sensor array; Exhaled breath;
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