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http://dx.doi.org/10.5369/JSST.2012.21.4.311

Development of Glucose Biosensor Using Sol-Gel Reaction of Tetraethoxysilane  

Chang, Seong-Cheol (Institute of BioPhysio Sensor Technology, Pusan National University)
Park, Deog-Su (Institute of BioPhysio Sensor Technology, Pusan National University)
Publication Information
Journal of Sensor Science and Technology / v.21, no.4, 2012 , pp. 311-317 More about this Journal
Abstract
Disposable amperometric screen-printed biosensor strips have been fabricated by a sol-gel encapsulation for the analysis of glucose. The glucose oxidase(GOx) is entrapped in the gel matrix through sol-gel transition of tetraethoxysliane(TEOS). The biosensor is fabricated by GOx containing thin film of TEOS gel on the surface of screen-printed carbon electrode(SPCE). The GOx-containing thin film of TEOS gel offers a one-step modification process on the surface of SPCE. The optimum conditions for glucose determination have been characterized with respect to the applied potential, enzyme loading ratio, and pH. The linear range and detection limit of glucose detection were from 2.0 mM to 16.0 mM and 0.25 mM, respectively.
Keywords
Sol-Gel; Glucose; Biosensor; Alkoxysilane; Amperometry;
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