Browse > Article
http://dx.doi.org/10.5369/JSST.2012.21.2.90

ISFET Glucose Sensor with Palladium Hydrogen Selective Membrane  

Chung, Mi-Kyung (Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST))
Kim, Seong-Wan (Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST))
Lee, Sang-Sik (Department of Biomedical Engineering, Kwandong University)
Park, Chong-Ook (Department of Materials Science and Engineering, Korea Advanced Institute of Science and Technology (KAIST))
Publication Information
Journal of Sensor Science and Technology / v.21, no.2, 2012 , pp. 90-95 More about this Journal
Abstract
This paper describes the development of a glucose biosensor based on ion sensitive field effect transistor(ISFET) with a palladium(Pd) modified ion sensing membrane. By adopting Pd as a hydrogen sensitive layer and integrating a screen-printed reference electrode, the sensitivity and stability were considerably improved due to the high permeability and selectivity of the Pd hydrogen selective membrane. This paper suggests a new approach for realizing portable and highly sensitive glucose sensors for diagnosing and treating diabetes mellitus.
Keywords
Glucose sensor; ISFET; Palladium; Semiconductor Biosensor;
Citations & Related Records
연도 인용수 순위
  • Reference
1 K.I. Lundstrom, M.S. Shivaraman, and C.M. Svensson, "A hydrogen-sensitive Pd-gate MOS transistor", J. Appl. Phys., vol. 46, no. 9, pp. 3876- 3881, 1975.   DOI   ScienceOn
2 R. Kirchheim and R.B. McLellan, "Electrochemical methods for measuring diffusivities of hydrogen in palladium and palladium alloys", J. Electrochem. Soc., vol. 127, no. 11, pp. 2419-2425, 1980.   DOI
3 V. Volotovsky, A.P. Soldatkin, A.A. Shulga, V.K. Rossokhaty, V.I. Strikha, and A.V. Elskaya, "Glucose-sensitive ion-sensitive field-effect transistorbased biosensor with additional positively charged membrane Dynamic range extension and reduction of buffer concentration influence on the sensor response", Anal. Chim. Acta, vol. 322, no. 1-2, pp. 77- 81, 1996.   DOI   ScienceOn
4 P. Bergveld, "Development, operation, and application of the ion-sensitive field-effect transistor as a tool for electrophysiology", IEEE Trans. Biomed. Eng., vol. BME-19, no. 5, pp. 342-351, 1972.   DOI   ScienceOn
5 M.W. Shinwari, M.J. Deen, and D. Landheer, "Study of the electrolyte-insulator-semiconductor field-effect transistor(EISFET) with applications in biosensor design", Microelectron. Reliab., vol. 47, no.12, pp. 2025-2057, 2007.   DOI   ScienceOn
6 A.A. Shulga, A.C. Sandrovsky, V.I. Strikha, A.P. Soldatkin, N.F. Starodub, and A.V. Elskaya, "Overall characterization of ISFET-based glucose biosensor", Sens. Actuators B, vol. 10, no. 1, pp. 41-46, 1992.   DOI   ScienceOn
7 A.K. Covington and P.D. Whalley, "Recent advances in microelectronic ion-sensitive devices(ISFETs)", J. Chem. Soc., Faraday Trans. 1, vol. 82, pp. 1209-1215, 1986.   DOI
8 S.V. Dzyadevych, A.P. Soldatkin, A.V. El'skaya, C. Martelet, and N. Jaffrezic-Renault, "Enzyme biosensors based on ion-selective field-effect transistors", Anal. Chim. Acta, vol. 568, no. 1-2, pp. 248-258, 2006.   DOI   ScienceOn
9 M.J. Schoning and A. Poghossian, "Recent advances in biologically sensitive field-effect transistors (BioFETs)", Analyst, vol. 127, no. 9, pp. 1137-1151, 2002.   DOI   ScienceOn
10 I. Lundstrom, C. Nylander, and A. Spetz, "Palladiumsilicondioxide- silicon structures as hydrogen sensors in electrolytes", Electron. Lett., vol. 19, no.7, pp. 249- 251, 1983.   DOI   ScienceOn
11 K.M.V. Narayan, J.B. Saaddine, J.P. Boyle, T.J. Thompson, and L.S. Geiss, "Impact of recent increase in incidence on future diabetes burden", Diabetes Care, vol. 29, no. 9, pp. 2114-2116, 2006.   DOI   ScienceOn
12 Q.J. Chi and S.J. Dong, "Flow-injection analysis of glucose at an amperometric glucose sensor based on electrochemical deposition of palladium and glucose oxidase on a glassy carbon electrode", Anal. Chim. Acta, vol.278, no.1, pp. 17-23, 1993.   DOI   ScienceOn
13 S.H. Lim, J. Wei, J.Y. Lin, Q.T. Li, and J. KuaYou, "A glucose biosensor based on electrodeposition of palladium nanoparticles and glucose oxidase onto Nafion-solubilized carbon nanotube electrode", Biosens. Bioelectron., vol. 20, no. 11, pp. 2341-2346, 2005.   DOI   ScienceOn
14 Z. Shi and J.A. Szpunar, "Synthesis of an ultra-thin palladium membrane for hydrogen extraction", Rev. Adv. Mater. Sci., vol. 15, no.1, pp. 1-9, 2007.
15 E.H. Yoo and S.Y. Lee, "Glucose biosensors: an overview of use in clinical practice", Sensors, vol. 10, no. 5, pp. 4558-4576. 2010.   DOI   ScienceOn
16 P. Bergveld, "Development of an ion-sensitive solidstate device for neurophysiological measurements", IEEE Trans. Biomed. Eng., vol. BME-17, no. 1, pp. 70- 71, 1970.   DOI
17 A. Heller and B. Feldman, "Electrochemical glucose sensors and their applications in diabetes management", Chem. Rev., vol. 108, no. 7, pp. 2482-2505, 2008.   DOI   ScienceOn
18 S.V. Dzyadevych, A.P. Soldatkin, Y.I. Korpan, V.N. Arkhypova, A.V. El'skaya, J.M. Chovelon, C. Martelet, and N. Jaffrezic-Renault, "Biosensors based on enzyme field-effect transistors for determination of some substrates and inhibitors", Anal. Bioanal.Chem., vol. 377, no. 3, pp. 496-506, 2003.   DOI
19 N. Jaffrezic-Renault and C. Martelet, "Semiconductorbased micro-biosensors", Synth. Met., vol. 90, no. 3, pp. 205-210, 1997.   DOI   ScienceOn