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http://dx.doi.org/10.5369/JSST.2009.18.2.139

Extremely large-area travelling-wave dielectrophoresis microbead separator using a multilayered bus bar  

Choi, Eun-Pyo (Department of Mechanical Engineering, Sogang University)
Kim, Byung-Kyu (School of Aerospace and Mechanical Engineering, Korea Aerospace University)
Park, Jung-Yul (Department of Mechanical Engineering, Sogang University)
Publication Information
Journal of Sensor Science and Technology / v.18, no.2, 2009 , pp. 139-146 More about this Journal
Abstract
A Multilayered microelectrode design is presented for large area travelling wave dielectrophoresis (TwDEP) separators. Most of typical TwDEP chip has been arrayed with 1000 electrodes in $20{\times}20\;mm^2$. However, there is a limitation of the device area that is critical in throughput, because when the area of TwDEP becomes larger, the resistance of microelectrodes for bus bar is also increased. In this paper, we successfully developed a novel TwDEP chip with extremely large area ($31{\times}25\;mm^2$) by a unique multilayered bus bar design. According to the resistance simulation of our microelectrodes, it is possible to realize a TwDEP chip with an infinite longitudinal length. We demonstrated the feasibility of our suggestion with latex microbeads and showed the potential of extremely high throughput separation with TwDEP technique.
Keywords
dielectrophoresis; travelling wave dielectrophoresis; high throughput; lab-on-a-chip;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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1 H. Morgan, A. G. Izquierdo, D. Bakewell, N. G. Green, and A. Ramos, 'The dielectrophoretic and travelling wave forces generated by interdigitated electrode arrays : analytical solution using Fourier series', J. Physics D-Applied Physics, vol. 34, pp. 1553-1561, 2001   DOI   ScienceOn
2 R. Pethig, M. S. Talary, and R. S. Lee, 'Enhancing traveling-wave dielectrophoresis with signal superposition', IEEE Engineering in Medicine and Biology Magazine, vol. 22, pp. 43-50, 2003
3 Y. J. Zhao, U. C. Yi, and S. K. Cho, 'Microparticle concentration and separation by traveling-wave dielectrophoresis (twDEP) for digital microfluidics', J. Microelectromechanical Systems, vol. 16, pp. 1472-1481, 2007   DOI   ScienceOn
4 R. Pethig, J. P. H. Burt, A. Parton, N. Rizvi, M. S. Talary, and J. A. Tame, 'Development of biofactoryon- a-chip technology using excimer laser micromachining', J. Micromechanics and Microengineering, vol. 8, pp. 57-63, 1998   DOI   ScienceOn
5 H. B. Li and R. Bashir, 'Dielectrophoretic separation and manipulation of live and heat-treated cells of Listeria on microfabricated devices with interdigitated electrodes', Sensors and Actuators B-Chemical, vol. 86, pp. 215-221, 2002   DOI   ScienceOn
6 G. Fuhr, R. Hagedorn, T. Muller, W. Benecke, B. Wagner, and J. Gimsa, 'Asynchronous travelingwave induced linear motion of living cells', Studia Biophysica, vol. 140, pp. 79-102, 1991
7 Y. Huang, X. B. Wang, J. A. Tame, and R. Pethig, 'Electrokinetic behavior of colloidal particles in traveling electric-fields - studies using yeast-cells', J. Physics D-Applied Physics, vol. 26, pp. 1528-1535, 1993   DOI   ScienceOn
8 M. S. Talary, J. P. H. Burt, J. A. Tame, and R. Pethig, 'Electromanipulation and separation of cells using travelling electric fields', J. Physics DApplied Physics, vol. 29, pp. 2198-2203, 1996   DOI   ScienceOn
9 N. G. Green, M. P. Hughes, W. Monaghan, and H. Morgan, 'Large area multilayered electrode arrays for dielectrophoretic fractionation', Microelectronic Engineering, vol. 35, pp. 421-424, 1997   DOI   ScienceOn
10 H. Morgan, N. G. Green, M. P. Hughes, W. Monaghan, and T. C. Tan, 'Large-area travelling-wave dielectrophoresis particle separator', J. Micromechanics and Microengineering, vol. 7, pp. 65-70, 1997   DOI   ScienceOn
11 X. B. Wang, Y. Huang, X. J. Wang, F. F. Becker, and P. R. C. Gascoyne, 'Dielectrophoretic manipulation of cells with spiral electrodes', Biophysical Journal, vol. 72, pp. 1887-1899, 1997   DOI   ScienceOn
12 L. Cui and H. Morgan, 'Design and fabrication of travelling wave dielectrophoresis structures', J. Micromechanics and Microengineering, vol. 10, pp. 72-79, 2000   DOI   ScienceOn
13 L. Cui, D. Holmes, and H. Morgan, 'The dielectrophoretic levitation and separation of latex beads in microchips', Electrophoresis, vol. 22, pp. 3893- 3901, 2001   DOI   ScienceOn
14 P. R. C. Gascoyne, X. B. Wang, Y. Huang, and F. F. Becker, 'Dielectrophoretic separation of cancer cells from blood', Ieee Transactions on Industry Applications, vol. 33, pp. 670-678, 1997   DOI   ScienceOn
15 김동일, 최은표, 최성식, 박정열, 이상호, 윤광석, '임피던스 측정을 이용한 세포의 변형성 분석용 미소유체 칩', 센서학회지, 제18권, 제1호, pp. 42-47, 2009   과학기술학회마을   DOI
16 최성용, 박제균, '유체영동 기반의 입자분리현상을 이용한 세포 크기 측정방법', 센서학회지, 제17권, 제4호, pp. 245-249, 2008   DOI
17 J. Park, B. Kim, S. K. Choi, S. Hong, S. H. Lee, and K. I. Lee, 'An efficient cell separation system using 3D-asymmetric microelectrodes', Lab on a Chip, vol. 5, pp. 1264-1270, 2005   DOI   ScienceOn