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http://dx.doi.org/10.5369/JSST.2008.17.1.029

Tri-enzyme modified electrochemical biosensor for paracetamol detection  

Park, Deog-Su (Center for Innovative Bio. Physio Sensor Technology, Pusan National University)
Shim, Yoon-Bo (Department of Chemistry, Pusan National University)
Chang, Seung-Cheol (Center for Innovative Bio. Physio Sensor Technology, Pusan National University)
Publication Information
Journal of Sensor Science and Technology / v.17, no.1, 2008 , pp. 29-34 More about this Journal
Abstract
A new disposable amperometric tri-enzyme biosensor for the detection of paracetamol has been developed. The paracetamol sensors developed uses horseradish peroxidase modified screen-printed carbon electrodes (HRP-SPCEs) coupled with immobilized enzymes, tyrosinase and aryl acylamidase, prepared using a poly (vinyl alcohol) bearing styrylpyridinium groups (PVA-SbQ) matrix. Optimization of the experimental parameters has been performed and the paracetamol biosensor showed detection limit for paracetamol is as low as $100{\mu}M$ and the sensitivity of the sensor is $1.46nA{\mu}M^{-1}cm^{-2}$.
Keywords
paracetamol; screen printing; amperometric and enzyme electrode;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
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