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http://dx.doi.org/10.5369/JSST.2006.15.1.028

Fiber-optic biosensor for analysis of glucose and lactate in blood samples  

Sohn, Ok-Jae (Bioprocess Technology Lab., Chonnam National University)
Rhee, Jong-Il (School of Applied Chemical Engineering, Chonnam National University)
Publication Information
Journal of Sensor Science and Technology / v.15, no.1, 2006 , pp. 28-33 More about this Journal
Abstract
Optical-fiber sensors have been developed to determine the concentrations of glucose and lactic acid in blood samples. Fluorescence dye [tris(2,2'-biphenyridine)-ruthenium(II)-chloride (RuBPY)] was entrapped by using a silicon to the unclad tip of a glass optic fiber. Enzymes like glucose oxidase (GOD) and lactate oxidase (LOD) have been immobilized by acrylamide resin adhesive, adsorption with zeolite or covalent bonding with aminopropyl-triethoxysilan. The fiber-optic glucose/lactate sensor was then used to analyze the concentrations of glucose and lactate in blood samples. The results were compared with the results of HPLC analysis and their difference was in error by less then 5 %.
Keywords
fiber-optic biosensor; glucose; lactate; blood samples;
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Times Cited By KSCI : 2  (Citation Analysis)
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