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http://dx.doi.org/10.14776/piv.2019.26.e14

Postinfectious Glomerulonephritis Associated with Pneumococcus and Influenza A Virus Infection in a Child: a Case Report and Literature Review  

Huh, Homin (Department of Pediatrics, Seoul National University Children's Hospital)
Lee, Joon Kee (Department of Pediatrics, Seoul National University College of Medicine)
Yun, Ki Wook (Department of Pediatrics, Seoul National University Children's Hospital)
Kang, Hee Gyung (Department of Pediatrics, Seoul National University Children's Hospital)
Cheong, Hae Il (Department of Pediatrics, Seoul National University Children's Hospital)
Publication Information
Pediatric Infection and Vaccine / v.26, no.2, 2019 , pp. 118-123 More about this Journal
Abstract
Postinfectious glomerulonephritis (PIGN) is most commonly caused by Streptococcus pyogenes in children, but PIGN associated with other pathogens has been described in the literature. A previously healthy 6-year-old boy was admitted with complaints of cough, fever, and right chest pain. The patient was diagnosed with pneumococcal bacteremia and influenza A virus infection and treated with antibiotics and antiviral agent. During hospitalization, generalized edema, hematuria, proteinuria, and increased blood pressure were observed; therefore, we started administering diuretics. The boy was discharged with gross hematuria, and even microscopic hematuria disappeared 14 weeks after discharge. We report a case of PIGN associated with bacteremic pneumococcal pneumonia and influenza A virus infection in children. A urine test and blood pressure measurement should be considered for the early detection of PIGN in children with pneumococcal or influenza A virus infection when they present with nephritic symptoms.
Keywords
Streptococcus pneumoniae; Glomerulonephritis; Influenza; Pneumonia; Children;
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1 Eison TM, Ault BH, Jones DP, Chesney RW, Wyatt RJ. Post-streptococcal acute glomerulonephritis in children: clinical features and pathogenesis. Pediatr Nephrol 2011;26:165-80.   DOI
2 Hyman LR, Jenis EH, Hill GS, Zimmerman SW, Burkholder PM. Alternative C3 pathway activiation in pneumococcal glomerulonephritis. Am J Med 1975;58:810-4.   DOI
3 Odaka J, Kanai T, Ito T, Saito T, Aoyagi J, Betsui H, et al. A case of post-pneumococcal acute glomerulonephritis with glomerular depositions of nephritis-associated plasmin receptor. CEN Case Rep 2015;4:112-6.   DOI
4 Carceller Lechon F, de la Torre Espi M, Porto Abal R, Ecija Peiro JL. Acute glomerulonephritis associated with pneumonia: a review of three cases. Pediatr Nephrol 2010;25:161-4.   DOI
5 Schachter J, Pomeranz A, Berger I, Wolach B. Acute glomerulonephritis secondary to lobar pneumonia. Int J Pediatr Nephrol 1987;8:211-4.
6 Wolach B, Uziel Y, Berger I, Pomeranz A. Cat-scratch bacillus and Streptococcus pneumoniae causing submandibular suppurative adenitis and acute glomerulonephritis. Child Nephrol Urol 1990;10:158-60.
7 Phillips J, Palmer A, Baliga R. Glomerulonephritis associated with acute pneumococcal pneumonia: a case report. Pediatr Nephrol 2005;20:1494-5.   DOI
8 Hibino S, Hoshino A, Fujii T, Abe Y, Watanabe S, Uemura O, et al. Post-streptococcal acute glomerulonephritis associated with pneumococcal infection. Pediatr Int 2013;55:e136-8.   DOI
9 Ismail IH, Zainudin Z, Othman N. Pneumococcal glomerulonephritis in a healthy child: a case report and literature review. Singapore Med J 2014;55:e69-72.   DOI
10 Kaehny WD, Ozawa T, Schwarz MI, Stanford RE, Kohler PF, McIntosh RM. Acute nephritis and pulmonary alveolitis following pneumococcal pneumonia. Arch Intern Med 1978;138:806-8.   DOI
11 Gunasekaran K, Krishnamurthy S, Mahadevan S, Harish BN, Kumar AP. Clinical characteristics and outcome of post-infectious glomerulonephritis in children in southern India: a prospective study. Indian J Pediatr 2015;82:896-903.   DOI
12 Srivastava T, Warady BA, Alon US. Pneumonia-associated acute glomerulonephritis. Clin Nephrol 2002;57:175-82.   DOI
13 Laso MC, Cadario ME, Haymes L, Grimoldi I, Balbarrey Z, Casanueva E. Mycoplasma pneumoniae detection with PCR in renal tissue of a patient with acute glomerulonephritis. Pediatr Nephrol 2006;21:1483-6.   DOI
14 Jain T, Hemington L, Etuwewe B. A case of post-infectious glomerulonephritis following infection with influenza A subtype H1N1. Pediatr Nephrol 2011;26:151-2.   DOI