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http://dx.doi.org/10.14776/piv.2018.25.e10

Knowledge, Attitude and Practice on Maternal Immunization with Tetanus Toxoid, Reduced Diphtheria Toxoid, and Aellular Pertussis (Tdap) among Pregnant Women  

Lee, Shin-Hye (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Jin, Bo-Kyeung (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Baek, Kyeung-Suk (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Cho, Yong-Sun (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Lee, Taek-Jin (Department of Pediatrics, CHA Bundang Medical Center, CHA University School of Medicine)
Publication Information
Pediatric Infection and Vaccine / v.25, no.3, 2018 , pp. 141-147 More about this Journal
Abstract
Purpose: Despite effectiveness and safety of maternal tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis (Tdap) vaccination, Tdap vaccination coverage during pregnancy remains quite low. We assessed the knowledge, attitude and practice on maternal Tdap vaccination among pregnant women. Methods: This study was a cross-sectional survey of pregnant women who visited tertiary obstetrics and gynecologic units in Seoul and Gyeonggi province of Korea. Individual questionnaires were administered to assess knowledge, attitude and practice on maternal immunization with Tdap. Results: The questionnaires were completed by 184 pregnant women; 158 (86%) had not received information from doctors about pertussis and Tdap, and 166 (90%) did not know the need for Tdap vaccination. Only 7% of pregnant women unlikely to receive Tdap vaccine during current pregnancy answered 3 or more of the 5 knowledge-based questions correctly. By logistic regression analysis, recommendation by doctor (adjusted odd ratio [OR], 236.2; 95% confidence interval [CI], 12.6-4,432), belief that the vaccine is effective (adjusted OR, 40.21; 95% CI, 2.35-687.7), and belief that the vaccine is safe (adjusted OR, 19.83; 95% CI, 1.54-255.9) were significantly important factors to respondents' intention to be vaccinated. Conclusions: Most pregnant women seem to be neither recommended nor adequately informed about Tdap vaccination. Information given by health care professionals is very important to increase Tdap coverage among pregnant women.
Keywords
Pertussis; Immunization; Pregnancy; Attitude;
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1 Amirthalingam G, Andrews N, Campbell H, Ribeiro S, Kara E, Donegan K, et al. Effectiveness of maternal pertussis vaccination in England: an observational study. Lancet 2014;384:1521-8.   DOI
2 Gall SA, Myers J, Pichichero M. Maternal immunization with tetanus-diphtheria-pertussis vaccine: effect on maternal and neonatal serum antibody levels. Am J Obstet Gynecol 2011;204:334.e1-5.   DOI
3 Leuridan E, Hens N, Peeters N, de Witte L, Van der Meeren O, Van Damme P. Effect of a prepregnancy pertussis booster dose on maternal antibody titers in young infants. Pediatr Infect Dis J 2011;30:608-10.   DOI
4 Winter K, Cherry JD, Harriman K. Effectiveness of prenatal tetanus, diphtheria, and acellular pertussis vaccination on pertussis severity in infants. Clin Infect Dis 2017;64:9-14.   DOI
5 Winter K, Nickell S, Powell M, Harriman K. Effectiveness of prenatal versus postpartum tetanus, diphtheria, and acellular pertussis vaccination in preventing infant pertussis. Clin Infect Dis 2017;64:3-8.   DOI
6 Kharbanda EO, Vazquez-Benitez G, Lipkind HS, Klein NP, Cheetham TC, Naleway A, et al. Evaluation of the association of maternal pertussis vaccination with obstetric events and birth outcomes. JAMA 2014;312:1897-904.   DOI
7 Donegan K, King B, Bryan P. Safety of pertussis vaccination in pregnant women in UK: observational study. BMJ 2014;349:g4219.   DOI
8 Moro PL, McNeil MM, Sukumaran L, Broder KR. The Centers for Disease Control and Prevention's public health response to monitoring Tdap safety in pregnant women in the United States. Hum Vaccin Immunother 2015;11:2872-9.   DOI
9 Choi WS, Choi JH, Kwon KT, Seo K, Kim MA, Lee SO, et al. Revised adult immunization guideline recommended by the Korean society of infectious diseases, 2014. Infect Chemother 2015;47:68-79.   DOI
10 Seo J, Lim J. Trends in influenza vaccination coverage rates in South Korea from 2005 to 2014: effect of public health policies on vaccination behavior. Vaccine 2018;36:3666-73.   DOI
11 Noh JY, Seo YB, Song JY, Choi WS, Lee J, Jung E, et al. Perception and attitudes of Korean obstetricians about maternal influenza vaccination. J Korean Med Sci 2016;31:1063-8.   DOI
12 The Korean Pediatric Society. DTaP, Tdap, Td vaccine. In: Lee HJ, editor. Immunization guideline. 8th ed. Seoul: The Korean Pediatric Society, 2015:187-202.
13 Tanaka M, Vitek CR, Pascual FB, Bisgard KM, Tate JE, Murphy TV. Trends in pertussis among infants in the United States, 1980-1999. JAMA 2003;290:2968-75.   DOI
14 Centers for Disease Control and Prevention (CDC). Updated recommendations for use of tetanus toxoid, reduced diphtheria toxoid, and acellular pertussis vaccine (Tdap) in pregnant women--Advisory Committee on Immunization Practices (ACIP), 2012. MMWR Morb Mortal Wkly Rep 2013;62:131-5.
15 Choe YJ, Park YJ, Jung C, Bae GR, Lee DH. National pertussis surveillance in South Korea 1955-2011: epidemiological and clinical trends. Int J Infect Dis 2012;16:e850-4.   DOI
16 Kim IS, Seo YB, Hong KW, Noh JY, Choi WS, Song JY, et al. Perceptions of tetanus-diphteria-acellular pertussis (Tdap) vaccination among Korean women of childbearing age. Infect Chemother 2013;45:217-24.   DOI
17 Ministry of Health and Welfare; Korea Centers for Disease Control & Prevention. Infectious Diseases Surveillance Yearbook, 2017. Cheongju: Korea Centers for Disease Control & Prevention; 2018.
18 Choe YJ, Kim JW, Park YJ, Jung C, Bae GR. Burden of pertussis is underestimated in South Korea: a result from an active sentinel surveillance system. Jpn J Infect Dis 2014;67:230-2.   DOI
19 Clark TA. Changing pertussis epidemiology: everything old is new again. J Infect Dis 2014;209:978-81.   DOI