Browse > Article
http://dx.doi.org/10.14776/piv.2015.22.1.1

An Outbreak of Mumps in a High School, Seoul, 2013  

Kang, Ha Ra (Department of Pediatrics, Eulji General Hospital)
Kim, Sung Yoon (Department of Pediatrics, Eulji General Hospital)
Cha, Hyo Hyun (Department of Pediatrics, Eulji General Hospital)
An, Young Min (Department of Pediatrics, Eulji General Hospital)
Park, In Ah (Nowon-Gu Health Care Center)
Kang, Hae Ji (Division of Respiratory Viruses, Korea National Institute of Health, Centers for Disease Control & Prevention)
Eun, Byung Wook (Department of Pediatrics, Eulji General Hospital)
Publication Information
Pediatric Infection and Vaccine / v.22, no.1, 2015 , pp. 1-6 More about this Journal
Abstract
Purpose: This study investigated an outbreak of mumps affecting students in a high school (S high school) in Seoul, with an evaluation of the diagnostic utility of the mumps polymerase chain reaction (PCR) assay. Methods: S high school students that presented to health care providers with mumps symptoms between April 2013 and July 2013 were surveyed for the monthly distribution of symptom onset and their grade level. Mumps PCR assays were performed using buccal swabs from some of these students. Results: During the survey period, 77 students presented with suspected cases of mumps. The monthly distribution of symptom onset was as follows: one in April, 17 in May, 54 in June, and five in July. With regard to grade level, 26 students were in their first year, 28 were in their second year, and 23 were in their third year. Of the 18 students tested with PCR assays, five had positive results. Samples were collected within 3 days of symptom onset in 15 of the 18 students, and positive PCR results were obtained in five of these 15 students. The PCR results of the remaining three students from whom samples were collected more than 3 days after the onset of symptoms were negative (P=0.24). Conclusions: We evaluated the epidemiological aspects of an outbreak of mumps in a high school. Mumps PCR might be epidemiologically useful if performed within 3 days of the onset of symptoms in suspected cases.
Keywords
Mumps; Outbreaks; Adolescent; Polymerase Chain Reaction;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
연도 인용수 순위
1 Park DW, Nam MH, Kim JY, Kim HJ, Sohn JW, Cho Y, et al. Mumps outbreak in a highly vaccinated school population: assessment of secondary vaccine failure using IgG avidity measurements. Vaccine 2007;25:4665-70.   DOI
2 Cho SY, Lee SY, Kang JH, Hwang HS. Mumps outbreak in Incheon, Korea, 2009. Korean J of Pediatr. 2010;53:67.   DOI
3 Kim KH, Kim CH, Choi BY, Go UY, Lee DH, Ki M. Mumps transmission control status and inapparent infection rate among middle and high school students during the 2007-2008 mumps outbreak in Daegu. J Prev Med Public Health 2009;42:408-15.   DOI
4 Korea Centers for Disease Control & Prevention. Infectious Diseases Surveillance Yearbook, 2013. Public Health Weekly Report 2014;6:79-81. Available at http://www.cdc.go.kr/CDC/info/CdcKrInfo0302.jsp?menuIds=HOME001-MNU1132-MNU1138-MNU0038&fid=32&q_type=&q_value=&cid=27068&pageNum=
5 American Academy of Pediatrics. Mumps. In: Pickering LK, Baker CJ, Kimberlin DW, Long SS, editors. Red Book: 2012 Report of the Committee on Infectious Diseases. 29th ed. Elk Grove Village, IL: American Academy of Pediatrics, 2012:514-8.
6 Korea Centers for Disease Control & Prevention. Division of VPD control & NIP Korea. Available at http://cdc.go.kr/CDC/intro/CdcKrIntro0201.jsp?menuIds=HOME001-MNU1154-MNU0005-MNU0011&cid=21959
7 Peltola H, Kulkarni PS, Kapre SV, Paunio M, Jadhav SS, Dhere RM. Mumps outbreaks in Canada and the United States: time for new thinking on mumps vaccines. Clin Infect Dis 2007;45:459-66.   DOI
8 Choi BY, Kim CH, Ki M, Lee SY, Kim CH, Kang C, et al. Development of goal and strategy of mumps vaccination program. Korea Centers for Disease Control and Prevention. 2005.
9 Ogbuanu IU, Kutty PK, Hudson JM, Blog D, Abedi GR, Goodell S, et al. Impact of a third dose of measles-mumpsrubella vaccine on a mumps outbreak. Pediatrics 2012;130:e1567-74.   DOI
10 Cherry JD. Mumps virus. In: Feigin RD, Cherry JD, Demmler GJ, Kaplan SL, editors. Feigin and Cherry's textbook of pediatric infectious diseases. 6th ed. Philadelphia, PA: Saunders/Elsevier; 2009;2451-69.
11 Rota JS, Rosen JB, Doll MK, McNall RJ, McGrew M, Williams N, et al. Comparison of the sensitivity of laboratory diagnostic methods from a well-characterized outbreak of mumps in New York city in 2009. Clin Vaccine Immunol 2013;20:391-6.   DOI
12 Manson WH. Mumps, In: Kliegman R, Nelson WE, editors. Nelson textbook of pediatrics. 19th ed. Philadelphia, PA: Elsevier/Saunders, 2011:1078-81.
13 The Korean Pediatric Society. Measles.Mumps.Rubella. In: Lee HJ, ed. Immunization guideline. 7th ed. Seoul: The Korean Pediatric Society; 2012:92-108
14 MacDonald N, Hatchette T, Elkout L, Sarwal S. Mumps is back: why is mumps eradication not working? In: N. Curtis et al, (Ed.) Hot topics in infection and immunity in children VII. Springer, New York; 2010:197-220.
15 Greenland K, Whelan J, Fanoy E, Borgert M, Hulshof K, Yap KB, et al. Mumps outbreak among vaccinated university students associated with a large party, the Netherlands, 2010. Vaccine 2012;30:4676-80.   DOI
16 Anis E, Grotto I, Moerman L, Warshavsky B, Slater PE, Lev B. Mumps outbreak in Israel's highly vaccinated society: are two doses enough. Epidemiol and Infect 2012;140:439-46.   DOI
17 Kim KH. Reemerging old infectious diseases: diagnosis of measles, mumps, rubella, and pertussis. Korean J Pediatr Infect Dis 2013;20:115-22.
18 Centers for Disease Control and Prevention. Mumps outbreak on a university campus-California, 2011. Morb Mortality Weekly Report 2012;61:986-9.
19 Dayan GH, Quinlisk MP, Parker AA, Barskey AE, Harris ML, Schwartz JM. Recent resurgence of mumps in the United states. N Engl J Med 2008;358:1580-9.   DOI