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http://dx.doi.org/10.14776/kjpid.2014.21.3.219

A Case of Late Onset Neonatal Bacteremia and Meningitis Caused by Streptococcus lutetiensis  

Kim, Ji Sook (Department of Pediatrics, Kosin University College of Medicine)
Hong, Yoo Ra (Department of Pediatrics, Kosin University College of Medicine)
Yang, Hee Yeong (Department of Laboratory Medicine, Kosin University College of Medicine)
Oh, Chi Eun (Department of Pediatrics, Kosin University College of Medicine)
Publication Information
Pediatric Infection and Vaccine / v.21, no.3, 2014 , pp. 219-224 More about this Journal
Abstract
Invasive infection of the Streptococcus bovis group in a neonate is rare. In cases reported to date, the pathogen of neonatal S. bovis infections is usually Streptococcus gallolyticus subsp. pasteurianus (S. bovis biotype II/2). Streptococcus lutetiensis (S. bovis biotype II/1) was identified using 16S rRNA and tuf gene sequence analysis of the isolates from blood and cerebrospinal fluid (CSF) of a fever-presenting 28-day-old male. Blood culture analysis was performed using automatic equipment (VITEK 2) and identified Streptococcus infantarius supsp. infantarius, yet we were unable to get accurate results from the CSF culture. The fever subsided on the second day of hospitalization, and the patient was discharged without neurologic complication after 14 days of antibiotic therapy. In this case, we were able to accurately identify the pathogen using molecular genetic methods. To our knowledge, this is the first case of late onset neonatal bacteremia and meningitis caused by S. lutetiensis.
Keywords
Streptococcus bovis; Newborn; Bacteremia; Meningitis;
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1 Schlegel L, Grimont F, Ageron E, Grimont PA, Bouvet A. Reappraisal of the taxonomy of the Streptococcus bovis/Streptococcus equinus complex and related species: description of Streptococcus gallolyticus subsp. gallolyticus subsp. nov., S. gallolyticus subsp. macedonicus subsp. nov. and S. gallolyticus subsp. pasteurianus subsp. nov. Int J Syst Evol Microbiol 2003;53:631-45.   DOI   ScienceOn
2 Heading DL, Herrera A, Mazzi E, Bergman MA. Fulminant neonatal septicemia caused by Streptococcus bovis. J Pediatr 1978;92:282-3.   DOI
3 Park JW, Kim YK, Eun SH, Kim EC, Seong MW. Neonatal invasive Streptococcus gallolyticus subsp. pasteurianus infection with delayed central nervous system complication. Korean J Pediatr 2013 in Press.
4 Gerber JS, Glas M, Frank G, Shah SS. Streptococcus bovis infection in young infants. Pediatr Infect Dis J 2006;25:1069-73.   DOI
5 Grant RJ, Whitehead TR, Orr JE. Streptococcus bovis meningitis in an infant. J Clin Microbiol 2000;38:462-3.
6 Al-Arishi H, Frayha HH, Yaneza AL, Al Hifzi IS. Isolated cerebrospinal fluid eosinophilia due to Streptococcus bovis meningitis in an infant. Int J Infect Dis 2002;6:323-5.   DOI
7 Cheung M, Pelot M, Nadarajah R, Kohl S. Neonate with late onset Streptococcus bovis meningitis: case report and review of the literature. Pediatr Infect Dis J 2000;19:891-3.   DOI
8 Okumura A, Takahashi H, Ogawa A, Kuno K, Watanabe K. Streptococcus bovis meningitis in an otherwise healthy infant. Clin Pediatr (Phila) 2002;41:523-4.   DOI
9 Koh TH, Ho S. Streptococcus bovis meningitis in a neonate with Ivemark syndrome. Scand J Infect Dis 2002;34:63-4.   DOI
10 Gavin PJ, Thomson RB Jr, Horng SJ, Yogev R. Neonatal sepsis caused by Streptococcus bovis variant (biotype II/2): report of a case and review. J Clin Microbiol 2003;41:3433-5.   DOI
11 Onoyama S, Ogata R, Wada A, Saito M, Okada K, Harada T. Neonatal bacterial meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. J Clin Microbiol 2009;58:1252.
12 Khan A. Relative penicillin resistance in Streptococcus bovis. A case of neonatal meningitis. J Paediatr Child Health 2009;45:474-5.   DOI
13 Kaltte JM, Clarridge JE 3rd, Bratcher D, Selvarangan R. A longitudinal case series description of meningitis due to Streptococcus gallolyticus subsp. pasteurianus in infants. J Clin Microbiol 2012;50:57-60.   DOI
14 Thatrimontrichai A, Chanvitan P, Janjindamai W, Dissaneevate S, Maneenil G. Early onset neonatal bacterial meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. Southeast Asian J Trop Med Public Health 2012;43:145-51.
15 Nagamatsu M, Takagi T, Ohyanagi T, Yamazaki S, Nobuoka S, Takemura H, et al. Neonatal bacterial meningitis caused by Streptococcus gallolyticus subsp. pasteurianus. J Infect Chemother 2012;18:265-8.   DOI
16 Floret N, Bailly P, Thouverez M, Blanchot C, Alez-Martin D, Menget A, et al. A cluster of bloodstream infections caused by Streptococcus gallolyticus subspecies pasteurianus that involved 5 preterm neonates in a university hospital during a 2-month period. Infect Control Hosp Epidemiol 2010;31:194-6.   DOI   ScienceOn
17 Nagai K, Gotoh K, Hirotaki S, Hidaka H, Koga H, Ikenaga M, et al. A case of bacterial meningitis due to Streptococcus bovis in an infant with normal cerebrospinal fluid findings at the first CSF examination. Kansenshogaku Zasshi 2008;82:26-9.   DOI
18 Binghuai L, Wenjun S, Xinxin L. Intrauterine infection and post-partum bacteraemia due to Streptococcus gallolyticus subsp. pasteurianus. J Med Microbiol 2013;62:1617-9.   DOI
19 Takahashi Y, Ishiwada N, Tanaka J, Okusu K, Ichimura S, Hishiki H, et al. Streptococcus gallolyticus subsp. pasteurianus meningitis in an infant. Pediatr Int 2014;56:282-5.   DOI
20 Beck M, Frodl R, Funke G. Comprehensive study of strains previously designated Streptococcus bovis consecutively isolated from human blood cultures and emended description of Streptococcus gallolyticus and Streptococcus infantarius subsp. coli. J Clin Micorobiol 2008;46:2966-72.   DOI   ScienceOn
21 Schlegel L, Grimont F, Collins MD, Regnault B, Grimont PA, Bouvet A. Streptococcus infantarius sp. nov., Streptococcus infantarius subsp. infantarius subsp. nov. and Streptococcus infantarius subsp. coli subsp. nov., isolated from humans and food. Int J Syst Evol Microbiol 2000;50:1425-34.   DOI   ScienceOn
22 Romero B, Morosini MI, Loza E, Rodriguez-Banos M, Navas E, Canton R, et al. Reidentification of Streptococcus bovis isolates causing bacteremia according to the new taxonomy criteria: still an issue? J Clin Microbiol 2011;49:3228-33.   DOI
23 Chapter 11. Disease of the Newborn. In: Ahn HS, editor. Hong Changeui Textbook of Pediatrics. 10th ed. Seoul: Mirae-N Co., Ltd, 2012:331-6.
24 Janda JM, Abbott SL. 16S rRNA gene sequencing for bacterial identification in the diagnostic laboratory: pluses, perils, and pitfalls. J Clin Microbiol 2007;45:2761-4.   DOI   ScienceOn
25 Haanpera M, Jalava J, Huovinen P, Meurman O, Rantakokko-Jalava K. Identification of alpha-hemolytic streptococci by pyrosequencing the 16S rRNA gene and by use of VITEK 2. J Clin Microbiol 2007;45:762-70.   DOI
26 Fikar CR, Levy J. Streptococcus bovis meningitis in a neonate. Am J Dis Child 1979;133:1149-50.