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Three Cases of Prevention Therapy to Reduce Perinatal HIV Transmission  

Lee, Jae Yo (Department of Pediatrics, National Medical Center)
Park, Hyang Mi (Department of Pediatrics, National Medical Center)
Hwang, Se Hee (Department of Pediatrics, National Medical Center)
Kim, Kyeung Eun (Department of Pediatrics, National Medical Center)
Shin, Hye Jung (Department of Pediatrics, National Medical Center)
Kim, Jae Yoon (Department of Pediatrics, National Medical Center)
Publication Information
Pediatric Infection and Vaccine / v.18, no.1, 2011 , pp. 85-90 More about this Journal
Abstract
In 2008, the Joint United Nations Programme on HIV/AIDS (UNAIDS) estimated that about 430,000 children worldwide became infected with HIV, mostly through mother-to-child transmission (MTCT) during pregnancy, labor, delivery, or breastfeeding. The MTCT prevention program proved to be feasible and effective in reduction of perinatal HIV transmission. Three babies born from HIV-infected mothers were admitted to the National Medical Center in 2009. Only two women received antiretroviral (ARV) therapy during pregnancy, labor, and after delivery, and their infants received zidovudine (AZT) for 6 weeks. The outcome, after a follow-up period of 4 months to 16 months, was favorable in all patients. Thus, we emphasize the need for expansion of antenatal HIV screening of pregnant women, implemented for early HIV diagnosis and effective ARV therapy for reduction of perinatal HIV transmission.
Keywords
HIV; Antiretroviral therapy;
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