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Nasal Carriage of Staphylococcus aureus from Healthy Children Attending Day Care Center  

Kim, Young Min (Department of Pediatrics, Seoul National University Children's Hospital)
Oh, Chi Eun (Department of Pediatrics, Seoul National University Children's Hospital)
Kim, So Hee (Department of Pediatrics, Seoul National University Children's Hospital)
Lee, Jina (Department of Pediatrics, Seoul National University Bundang Hospital)
Choi, Eun Hwa (Department of Pediatrics, Seoul National University Children's Hospital)
Lee, Hoan Jong (Department of Pediatrics, Seoul National University Children's Hospital)
Publication Information
Pediatric Infection and Vaccine / v.17, no.1, 2010 , pp. 9-15 More about this Journal
Abstract
Purpose : This study was performed to investigate the prevalence of Staphylococcus aureus (S. aureus) nasal carriage in Korean children attending day care centers. Methods : During September and October 2009, a survey for nasal carriage of S. aureus and methicillin-resistant S. aureus (MRSA) was conducted among children attending day care centers located in Seoul with questionnaire survey for evaluation of risk factors of acquisition of MRSA was obtained from their guardians. A culture of the anterior nares swabs using enrichment broth was executed for isolating S. aureus and oxacillin susceptibility was assessed by the disk diffusion method. Results : Out of the 428 children enrolled whose mean age was 55 months old, 163 (38.1%) were colonized with S. aureus. Of the 163 isolates, 40 (24.5%) were MRSA. The nasal carriage rate of S. aureus showed an increasing trend with increase of age. Based on the answer to the questionnaire, 9.2% and 3.6% of children had a recent history of hospitalization and surgery, respectively, and approximately 40% of children had a history of prescription of antibiotics within 1 year prior to enrollment. Of the 428 subjects, 40 (9.3%) were MRSA nasal carriers. Conclusion : S. aureus and MRSA carriage rate of children attending day care center in Korea was 38.1% and 9.3%, respectively. Continued surveillance for nasal carriage rate of S. aureus and MRSA (especially community-associated MRSA) is mandatory.
Keywords
Staphylococcus aureus; Methicillin resistance; Children; Community-associated; Nasal carriage;
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