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http://dx.doi.org/10.5668/JEHS.2018.44.2.188

Vitamin D intake and Diabetes Mellitus in Korean Adults  

Hwang, Yerin (Department of Preventive Medicine, Gachon University College of Medicine)
Kwak, Jung Hyun (Department of Preventive Medicine, Gachon University College of Medicine)
Kim, Junghoon (Department of Preventive Medicine, Gachon University College of Medicine)
Choi, Yoon-Hyeong (Department of Preventive Medicine, Gachon University College of Medicine)
Publication Information
Journal of Environmental Health Sciences / v.44, no.2, 2018 , pp. 188-195 More about this Journal
Abstract
Objectives: This study aimed to investigate the association between vitamin D deficiency and the risk of diabetes mellitus, and also examined whether their association is differed by sex and age. Methods: We analyzed the data from 28,135 subjects ${\geq}20years$ old who were registered for the Korea National Health and Nutrition Examination Survey (KNHANES) 2008-2014. Vitamin D was measured using serum 25-hydroxyvitamin D (25(OH)D) concentrations. Results: After adjusting for potential confounders (age, sex, education, income, total energy intake, smoking, physical activity, body mass index, and waist circumference), lower vitamin D was dose-dependently associated with a higher risk of diabetes mellitus (p-trend=0.004). When compared with the sufficient group (25(OH)D ${\geq}30ng/mL$), the severe deficient group (25(OH)D <10 ng/mL) had 1.46 (95% CI 1.11-1.94) odds ratio for the risk of diabetes mellitus. This association was markedly strong in men and adults aged ${\geq}40$, whereas no significant association was observed in women and adults aged <40. Conclusions: We found that vitamin D deficiency may be associated with an increased risk for diabetes mellitus in Korean adults. Our findings suggest that intake of higher vitamin D may help reduce the risk of diabetes mellitus.
Keywords
Diabetes mellitus; Korean adults; KNHANES; Vitamin D;
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