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http://dx.doi.org/10.5668/JEHS.2018.44.1.76

Development and Application of a Chemical Ranking and Scoring System for the Management of Endocrine Disrupting Chemicals  

Lim, Miyoung (Department of Environmental Health, Graduate School of Public Health, Seoul National University)
Park, Ji Young (Institute of Health and Environment, Seoul National University)
Ji, Kyunghee (Department of Occupational and Environmental Health, Yongin University)
Lee, Kiyoung (Department of Environmental Health, Graduate School of Public Health, Seoul National University)
Publication Information
Journal of Environmental Health Sciences / v.44, no.1, 2018 , pp. 76-89 More about this Journal
Abstract
Background: Exposure to endocrine disrupting chemicals (EDCs) has been considered one of the main causes of a range of endocrine diseases in modern society. An EDC priority list considering exposure, toxicity, and societal concern should be established for EDC management. Methods: The chemical ranking and scoring (CRS) system for EDCs was based on exposure, toxicity,and societal concern. The exposure score system was based on usage, circulation volume, bioaccumulation, and detection in consumer products. The toxicity score system was based on carcinogenicity and reproductive and developmental toxicity. The societal concern score system was based on domestic or international regulations and mass media reports. Results: A total of 165 EDCs were considered in the CRS system. The top-five priority EDCs were Bis(2-ethylhexyl) phthalate (DEHP), Benzene, Bisphenol A, Dibutyl phthalate (DBP) and Trichloroethylene. Phthalates, bisphenols and parabens were identified as priority chemical groups. Conclusion: We developed a CRS system for EDCs to identify priority EDCs for management. This will be a foundation to provide an EDC management plan based on scientific decision-making.
Keywords
Endocrine disrupting chemicals; chemical ranking and scoring; priority list; chemical management;
Citations & Related Records
Times Cited By KSCI : 3  (Citation Analysis)
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