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http://dx.doi.org/10.5668/JEHS.2016.42.6.385

Health Effect Assessment on Cleanup Workers of an Oil Spill in Yeosu  

Kim, Geunbae (Environmental Health Research Department National Institute of Environmental Research)
Kang, Tack Shin (Environmental Health Research Department National Institute of Environmental Research)
Yoon, Mira (Environmental Health Research Department National Institute of Environmental Research)
Jo, Hyejung (Environmental Health Research Department National Institute of Environmental Research)
Joo, Youngkyung (Environmental Health Research Department National Institute of Environmental Research)
Yu, Seung Do (Environmental Health Research Department National Institute of Environmental Research)
Lee, Bo Eun (Environmental Health Research Department National Institute of Environmental Research)
Publication Information
Journal of Environmental Health Sciences / v.42, no.6, 2016 , pp. 385-395 More about this Journal
Abstract
Objectives: The aim of this study was to assess exposure to VOCs and PAHs and the health effects on volunteers who participated in an oil spill cleanup in Yeosu. Methods: Atmospheric VOCs were evaluated in the vicinity of the accident site and questionnaire surveys were conducted to identify personal characteristics and acute health symptoms of clean-up workers seven days after the accident. The levels of metabolites of VOCs (t,t-MA, HA, PGA, MA, MHA) and PAHs (2-NAP, 1-OHP, 2-HF, 1-HPH), oxidative stress markers (TABARS, 8-OHdG) in the urine of workers were analyzed. Their correlation was determined by multiple regression analysis with SAS ver. 9.4. Results: Although the concentration of atmospheric VOCs in the residential areas were low at the time of survey, the levels of VOCs and PAHs metabolites in clean-up workers were higher than those in the control group after clean-up activities. The levels of urinary VOC and PAH metabolites were significantly increased after clean-up compared to those measured before participation. The thiobarbituric acid reactive substance (TBARS) concentrations were also increased and showed significant correlations with those of metabolites of benzene. Conclusion: This study shows that oil spill clean-up activities affect exposure to VOCs and PAHs and the health of clean-up workers. The results suggest the need for check-ups of participants in oil spill cleaning work.
Keywords
MDA; metabolites; oil spill; TBARS; VOCs & PAHs;
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1 Oliveria M, Slezakova K, Jose Alves M, Fernandes A, Teixeira JP, Delerue-Matos C, et al. Firefighters' exposure biomonitoring: Impact of firefighting activities on levels of urinary monohydroxyl metabolites. International Journal of hygiene and Environmental Health. 2016; 219: 857-866.   DOI
2 Lee SM, Ha M, Kim EJ, Jeong WC, Hur J, Park SG, et al. The effects of wearing protective devices among residents and volunteers participating in the cleanup of the Hebei Spirit oil spill. J Prev Med Public Health. 2009; 42(2): 89-95.   DOI
3 National Institute of Environmental Research. Integrated Analysis of data from the Korean National Environmental Health Survey (1st stage, 2009-2011) and establishment of national statistic calculation. 2011.
4 Konjin ZN, Azari MR, Shekoohi Y, Rahimzadeh M, Seyedi M. Efficacy of Urinary Hippuric acid as a Biomarker of Low Level Exposure to Toluene in Petroleum Depot Workers. Iternational journal of Occupational Hygiene. 13; 5(3): 139-143.
5 Hippuric Acid Levels in Paint Workers at Steel Furniture Manufacturers in Thailand. Safety and Health at Work. 2014; 5: 227-233.   DOI
6 Ha M, Kwon HJ, Cheong HK, Lim S, Yoo SJ, Kim EJ, et al. Urinary metabolites before and after cleanup and subjective symptoms in wolunteer participants in cleanup of the Hebei Spirit oil spill. Science of the Total Environment. 2012; 429: 167-173.   DOI
7 Petroleum HPV Testing Group. High production volume chemical challenge program: Test plan, crude oil category. Washington: Petroleum High Production Volume Testing Group; 2003. [cited 2008 Nov 21] Available from: www.petroleumhpv.org/Product_Categories/Crude_Oil/Final_Test-Plan_Crude%20Oil_11-21-03.pdf.
8 World Health Organization. Air Quality Guideline for Europe (Second Edition), http://euro.who.int/__data/assets/pdf_file/0005/74732/E71922.pdf
9 International Agency for Research on Cancer. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, LIST OF CLASSIFICATIONS, VOLUMES 1-117, http://monographs.iarc.fr/ENG/Classification/latest_classif.php
10 Bosch X. Exposure to oil spill has detrimental effect on clean-up workers' health. Lancet. 2003; 361(9352): 147.   DOI
11 Carrasco JM, Perez-Gomez B, Garcia-Mendizabal MJ, Lope V, Aragones N, Forjaz MJ, et al. Healthrelated quality of life and mental health in the medium-term aftermath of the prestige oil spill in Galiza (Spain): a cross-sectional study. BMC Public Health. 2007; 7: 245.   DOI
12 Janjua NZ, Kasi PM, Nawaz H, Farooqui SZ, Khuwaja UB, Najam-ul-Hassan, et al. Acute health effects of the Tasman Spirit oil spill on residents of Karachi, Pakistan. BMC Public Health. 2006; 6: 84.   DOI
13 Kivisto H, Pekari K, Aitio A. Analysis and stability of phenylglyoxylic acid and mandelic acids in the urine of styrene-exposed people. Int Arch Occup Environ Health. 1993; 64: 399-403.   DOI
14 Morita A, Kusaka Y, Deguchi Y, Moriuchi A, Nakanaga Y, Iki K, et al. Acute health problems among the people engaged in the cleanup of the Nakhodka oil spill. Environ Res. 1999; 81(3): 185-194.   DOI
15 Suarez B, Lope V, Perez-Gomez B, Aragones N, Rodriguez-Artalejo F, Marques F, et al. Acute health problems among subjects involved in the cleanup operation following the Prestige oil spill in Asturias and Cantabria (Spain). Environ Res. 2005; 99(3): 413-424.   DOI
16 Rodriguez-Trigo G, Zock JP, Isidro Montes I. Health effects of exposure to oil spills. Arch Bronconeumol. 2007; 43(11): 628-635.   DOI
17 Khan HA. A concise review of chromatographic methods for the analysis of benzene and its metabolites. Croatica Chemica Acta. 2006; 79(2): 169-175.
18 Siqueira ME, Paiva MJ. Hippuric acid in urine: reference values. Rev Saude Publica. 2002; 36(6): 723-727.   DOI
19 Langman JM. Xylene: Its toxicity, measurement of exposure levels, absorption, metabolism and clearance. Pathology. 1994; 26: 301-309.   DOI
20 Campo L, Rossella F, Fustinoni S. Development of a gas chromatography/mass spectrometry method to quantify several urinary monohydroxy metabolites of polycyclic aromatic hydrocarbons in occupationally exposed subjects. J. Chromatography B. 2008; 875: 531-540.   DOI
21 Yan H, Yankai X, Pengfei Z, Shanlei Q, Rencheng Z, Nianzu J, et al. Reproductive hormones in relation to polycyclic aromatic hydrocarbon(PAH) metabolites among non-occupational exposure of males. Sci Total Environ. 2010; 408: 768-773.   DOI
22 Jansen EHJM, Schenk E, den Engrlsman G, van de Verken G. Use of biomarkers in exposure assessment of polycyclic aromatic hydrocarbons. Clin Chem. 1995; 41(12): 1905-1906.
23 Jongeneelen FJ, Anzion RB, Henderson PT. Determination of hydroxylated metabolites of polycyclic aromatic hydrocarbons in urine. J Chromatogr. 1987; 413: 227-232.   DOI
24 Kim H, Cho SH, Kang JW, Kim YD, Nan HM, Lee CH, et al. Urinary 1-hydroxypyrene and 2-naphthol concentrations in male Koreans. Int Arch Occup Environ Health. 2001; 74(1): 59-62.   DOI
25 Lee CH, Park KH, Lee MJ, Choi WH, Kim H, Park CH, et al. Health Effect Assessment on Volunteers Involved in the Cleanup Operation Following the Hebei Spirit Oil Spill Along the Taean Coast, Korea. Korean J Occup Environ Med. 2010; 22(1): 11-19.
26 Floyd RA. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990; 11(9): 1447-1450.   DOI
27 Park JY, Kim DM, Kim BW, Kim YG, Kim IJ, Kim TH, et al. Oxidative Stress, Inflammation and Diabetic Complications. BioWave. 2004: 6(13).
28 National Institute of Environmental Research. Exposure assessment of subjects on the oil spill cleanup activity in Taean. 2008.
29 National Institute of Environmental Research. Analysis manual for environmental hazards in biological samples collected by the 1st stage of the KONEHS. 2012.
30 Khoschsorur GA, Winklhofer-Roob BM, Rabl H, Auer T, Peng Z, Schaur RJ. Evaluation of a sensitive HPLC method for the determination of malondialdehyde, and application of the method to different biological materials. Chromatographia. 2000; 52: 181-184.   DOI
31 Inaba Y. Koide S, Yokoyama K, Karube I. Development of urinary 8-hydroxy-2'-deoxyguanosine(8-OHdG) measurement method combined with SPE. Journal of Chromatographic Science. 2011; 49: 303-309.   DOI
32 World Health Organization. Biological Monitoring of Chemical Exposure in the Workplace Vol 1. Geneva : World Health Organization. 1996.
33 Ha M, Lee WJ, Lee S, Cheong HK. A literature review on health effects of exposure to oil spill. J Prev Med Public Health. 2008; 41(5): 345-354.   DOI
34 Campbell D, Cox D, Crum J, Foster K, Christie P, Brewster D. Initial effects of the grounding of the tanker Braer on health in Shetland. The Shetland Health Study Group. BMC Public Health. 1993; 307(6914): 1251-1255.
35 Lyons R, Temple J, Evans D. Acute health effects of the Sea Empress oil spill. J Epidemiol Community Health. 1999; 53: 306-310.   DOI
36 Carrasco JM, Lope V, Perez-Gomez B, Aragones N, Suarez B, Lopez-Abente G, et al. Association between health information, use of protective devices and occurrence of acute health problems in the Prestige oil spill clean-up in Asturias and Cantabria (Spain): a cross-sectional study. BMC Public Health. 2006; 6: 1.   DOI
37 Meo S, Al-Drees A, Rasheed S, Meo I, Al-Saadi M, Ghani H, et al. Health complaints among subjects involved in oil cleanup operations during oil spillage from a Greek tanker "Tasman Spirit". Int J Occup Med Environ Health. 2009; 22(2): 143-148.   DOI
38 BoogaardVOCs PJ, van Sittert NJ. Biological monitoring of exposure to benzene: a comparison between S-phenylmercapturic acid, trans, transmuconic acid, and phenol, Occupational and Environmental Medicine. 1995; 52: 611-620.   DOI
39 Gwack J, Lee JH, Kang YA, Chang K-J, Lee MS, Hong JY. Acute health effects among military personnel participating in the cleanup of the Hebei Spirit oil spill, 2007, in Taean county, Korea. Osong Public Heal Res Perspect. 2012; 3(4): 206-212.   DOI
40 King B, Gibbons J. Health Hazard Evaluation of Deepwater Horizon Response Workers (HETA 2010-0115 & 2010-0129-3138). Springfield, Virginia; 2011 p. 20.
41 Yacob AR, Zinalibdin MR. High Performance Liquid Chromatography Determination of Urinary Hippuric acid and Benzoic Acid as Indices for Glue Sniffer Urine, International Scholarly and Scientific Research & innovation., 2010; 4(2): 237-242.
42 WHO/Europe. Air Quality Guideline for Europe, Second Edition. 2000.
43 Jacobson GA, McLean S. Biological Monitoring of Low level Occupational Xylene Exposure and The Role of Recent Exposure, Ann. occup. Hyg., 2003; 47(4): 331-336.   DOI
44 Wheeler AJ, Dobbin NA, Heroux ME, Fisher M, Sun L, Khoury CF, et al. Urinary and breast milk biomarkers to assess exposure to naphthalene in pregnant women: an investigation of personal and indoor air sources, Environmental Health, 2014; 13: 30   DOI
45 Jongeneelen FJ. Benchmark Guideline for Urinary 1-Hydroxypyrene as Biomarker of Occupational Exposure to Policyclic Aromatic Hydrocarbons, Ann. occup. Hyg., 2001; 45(1): 3-13.   DOI