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http://dx.doi.org/10.5668/JEHS.2010.36.3.208

Nicotine Exposure in Green Tobacco Harvesters  

Lee, Yun-Keun (Wonjin Institute of Occupational and Environmental Health)
Kim, Won (Wonjin Institute of Occupational and Environmental Health)
Choi, In-Ja (Wonjin Institute of Occupational and Environmental Health)
Publication Information
Journal of Environmental Health Sciences / v.36, no.3, 2010 , pp. 208-214 More about this Journal
Abstract
Green tobacco sickness (GTS) is an illness associated with nicotine exposures among tobacco harvesters. The purposes of this study were to measure the concentration of nicotine residues on the hands and forearms of tobacco harvesters, and to compare the concentrations according to the harvesting task. Wipe samples from the both hands and forearms were obtained from 16 workers at three sampling times (before work, in the morning after harvesting leaves, and in the afternoon after binding leaves). The geometric means of the right and left hand nicotine levels in harvesting work were 0.70 and $0.61\;{\mu}g/cm^2$, respectively, which were substantial, if significantly lower than the corresponding levels in binding work of 5.19 and $1.50\;{\mu}g/cm^2$ (p=0.016). The overall combined nicotine levels for the hands (i.e., left and right) were significantly higher than those for the forearms (p=0.013). The results of this study therefore indicate that, for GTS prevention, waterproof gloves should be worn while harvesting.
Keywords
green tobacco sickness; tobacco; nicotine; wipe sample;
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1 Marquart, H., Brouwer, D. H. and van Hemmen, J. J. : Removing pesticides from hands with a simple washing procedure using soap and water. Journal of Occupational and Environmental Medicine, 44, 1075-1082, 2002.   DOI   ScienceOn
2 Centers for Disease Control and Prevention (CDC) : Green tobacco sickness in tobacco harvesters-Kentucky, 1992. Morbidity and Mortality Weekly Report, 42, 237-240, 1993.
3 Curwin, B. D., Hein, M. J., Sanderson, W. T., Nishioka, M. G. and Buhler, W. : Nicotine exposure and decontamination on tobacco harvesters' hands. The Annals of Occupational Hygiene, 49(5), 407-413, 2005.   DOI   ScienceOn
4 Curwin, B. D., Hein, M. J., Sanderson, W. T., Nishioka, M. and Buhler, W. : Acephate exposure and decontamination on tobacco harvesters' hands. Journal of Exposure Analysis and Environmental Epidemiology, 13(3), 203-210, 2003.   DOI   ScienceOn
5 Geno, P. W., Camann, D. E. and Harding, H. J. : Handwipe sampling and analysis procedure for the measurement of dermal contact with pesticides. Archives of Environmental Contamination and Toxicology, 30, 132-138, 1996.   DOI
6 Lee, K., Lim, H.-S., Kim, H. and Nam, S.-H. : Urinary cotinine concentrations of cases with green tobacco sickness. Korean Journal Occupational and Environmental Medicine, 16(4), 413-421, 2004.   과학기술학회마을
7 Rao, P., Quandt, S. A. and Arcury, T. A. : Hispanic farmworker interpretations of green tobacco sickness. The Journal of Rural Health, 18(4), 503-511, 2002.   DOI   ScienceOn
8 Food and Agriculture Organization of the United Nations (FAO). Available from : http://faostat.fao.org/. Cited Feb. 13, 2007.
9 Korea Tobacco Growers Cooperative Association (KTGCA). Available from : http://www.yyc.or.kr/yyc/. Cited Mar. 21, 2010.
10 Trape-Cardoso, M., Bracker, A., Grey, M., Kaliszewski, M., Oncken, C., Ohannessian, C., Barrera, L. V. and Gould, B. : Shade tobacco and green tobacco sickness in Connecticut. Journal of Occupational and Environmental Medicine, 45(6), 656-661, 2003.   DOI   ScienceOn
11 Trape-Cardoso, M., Bracker, A., Dauser, D., Oncken, C., Barrera, L. V., Gould, B. and Grey, M. R. : Cotinine levels and green tobacco sickness among shade-co sickness. Journal of Agromedicine, 1A(g2), 27-37, 2005.
12 Schmitt, N. M., Schmitt, J., Kouimintzis, D. J. and Kirch, W. : Health risks in tobacco farm workers-a review of the literature. Journal of Public Health, published on line, 1 June 2007.   DOI
13 Lee, K. and Lim, H.-S. : Prevalence and risk factors of Green Tobacco Sickness among Korean tobacco harvesters, 2003. Korean Journal of Epidemiology, 27(1), 129-139, 2005.   과학기술학회마을
14 Zorin, S., Kuylenstierna, F. and Thulin, H. : In vitro test of nicotine's permeability through human skin. Risk evaluation and safety aspects. The Annals of Occupational Hygiene, 43, 405-413, 1999.   DOI
15 Ghosh, S. K., Gokani, V. N., Doctor, P. B. and Parikh, J. R. : Intervention studies against "green symptoms" among Indian tobacco harvesters. Archives of Environmental Health, 46(5), 316-317, 1991.   DOI
16 Boylan, B. B., Brandt, V., Muehlbauer, J., Auslander, M. and Spurlock, C. : Green tobacco sickness in tobacco harvesters-Kentucky. Morbidity and Mortality Weekly Report, 42, 237-240, 1993.
17 Arcury, T. A., Quandt, S. A. and Preisser, J. S. : Predictors of incidence and prevalence of green tobacco sickness among Latino farmworkers in North Carolina. Journal of Epidemiology & Community Health, 55(11), 818-824, 2001.   DOI
18 Ballard, T., Ehlers, J., Freund, E., Auslander, M. and Brandt, V. : Green tobacco sickness: occupational nicotine poisoning in tobacco workers. Archives of Environmental Health, 50(5), 384-389, 1995.   DOI
19 Parikh, J. R., Gokani, V. N., Doctor, P. B., Kulkarni, P. K., Shah, A. R. and Saiyed, H. N. : Acute and chronic health effects due to green tobacco exposure in agricultural workers. American Journal of Industrial Medicine, 47, 494-499, 2005.   DOI   ScienceOn
20 American Conference of Governmental Industrial Hygienists (ACGIH) : Documentation of the threshold limit values and biological exposure indices, ACGIH, 2008.
21 Ellenhorn, M. J., Schonwald, S., Ordog, G. and Wasserberger, J. : Natural toxins. In; Ellenhorn MJ (eds.) Ellenhorn's Medical Toxicology: Diagnosis and Treatment of Human Poisoning. 2nd ed. Baltimore: Williams and Wilkins; 1997.
22 Fenske, R. A., Simcox, N. J. and Camp, J. E. : Comparison of three methods for assessment of hand exposure to azinphosmethyl(guthion) during apple thinning. Applied Occupational and Environmental Hygiene, 14, 618-623, 1999.   DOI
23 Arcury, T. A., Quandt, S. A., Garcia, D. I., Preisser, J. S. Jr, Norton, D. and Rah, P. : A clinic-based, casecontrol comparison of green tobacco sickness among minority farmworkers: clues for prevention. Southern Medical Journal, 95(9), 1008-1011, 2002.   DOI
24 Arcury, T. A., Quandt, S. A. and Preisser, J. S. : High levels of transdermal nicotine exposure produce green tobacco sickness in Latino farm workers. Nicotine & Tobacco Research, 5, 315-321, 2003.   DOI
25 Occupational Safety and Health Administration (OSHA) : Field Sanitation Standard. 29 CFR Part 1928.110. Washington, DC: Occupational Safety and Health Administration, U.S. Department of Labor, 1987.
26 Park, S.-J., Kim, J.-S., Kim, J.-S., Lee, K. and Lim, H.-S. : Airborne nicotine concentrations in harvesting and the processing of tobacco leaves. Journal of Korean Society Occupational and Environmental Hygiene, 20(1), 47-52, 2010.
27 Kim, H. C., Paik, N. W., Lee, K. S., Kim, K. R. and Kim, W. : A comparison of nicotine diffusive sampler and XAD-4 tube for determination of nicotine in ETS. Journal of Environmental Health Sciences, 32(5), 485-491, 2006.   과학기술학회마을
28 Weizenecker, R. and Deal, W. B. : Tobacco cropper's sickness. Journal of the Florida Medical Association, 57, 13-14, 1970.
29 Brouwer, D. H., Boeniger, M. F. and Hemmen, J. V. : Hand wash and manual skin wipes. Annals of Occupational Hygiene, 44, 501-510, 2000.   DOI
30 Environmental Protection Agency (EPA) : Exposure factors handbook, Volume 1: General factors. EPA/ 600/P-95/002Fa Washington, DC: Office of Research and Development, National Center for Environmental Assessment, U.S. Environmental Protection Agency, 1997.
31 Benowitz, N. L., Lake, T., Keller, K. H. and Lee, B. L. : Prolonged absorption with development of tolerance to toxic effects after cutaneous exposure to nicotine. Clinical Pharmacology & Therapeutics, 42(1), 119-120, 1987.   DOI
32 Arcury, T. A., Quandt, S. A., Preisser, J. S., Bernert, J. T., Norton, D. and Wang, J. : High levels of transdermal nicotine exposure produce green tobacco sickness in Latino farmworkers. Nicotine & Tobacco Research, 5(3), 315-321, 2003b.   DOI
33 Korea Tomorrow and Global (KT&G) : Standard planting method of green tobacco, Korea Tomorrow and Global, Seoul, 67-68, 2006.
34 Misumi, J., Koyama, W. and Miura J. : 2 cases of green tobacco disease among tobacco harvesters and percutaneous nicotine absorption in rats. Sangyo Igaku, 25(1), 3-9, 1983.   DOI   ScienceOn
35 Onuki, M., Yokoyama, K., Kimura, K., Sato, H., Nordin, R. B. and Naing, L. : Assessment of urinary cotinine as a ma urinof nicotine absorption from tobacco leaves: a study on tobacco farmers in Malaysia. Journal of Occupational Health, 45(3), 140-145, 2003.   DOI   ScienceOn
36 Lee, K. and Lim, H.-S. : Green Tobacco Sickness on tobacco harvesters in Korean village. Korean Journal of Epidemiology, 24(1), 29-36, 2002.