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http://dx.doi.org/10.5668/JEHS.2009.35.5.362

Antibacterial effects of Mume Fructus Water Extract against Salmonella typhimurium in Murine Salmonellosis  

Jung, Won-Chul (Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University)
Cha, Chun-Nam (Engineering Research Institute, Department of Industrial Systems Engineering, Gyeongsang National University)
Lee, Hu-Jang (Research Institute of Live Sciences, College of Veterinary Medicine, Gyeongsang National University)
Publication Information
Journal of Environmental Health Sciences / v.35, no.5, 2009 , pp. 362-364 More about this Journal
Abstract
The present study was undertaken to estimate the antibacterial effect of Mume Fructus water extract (MFWE) against murine salmonellosis. At MFWE concentrations ranging from 25 to 100 ${\mu}g/ml$, the antibacterial effect was not showed on Salmonella typhimurium (S. typhimurium). On the other hand, bacteria without MFWE had a tendency to proliferate up to 8 h after incubation. Oral administration of MFWE at the dose of 40 mg/ml showed a therapeutic effect for S. typhimurium infected BALB/c mice. The mortality of MFWE-treated mice was 80% at 12 days, while that of MFWE-untreated mice was 100% at 9 days after a lethal dose of S. typhimurium infection. The results of our study strongly indicate that MFWE has potential as an effective of salmonellosis.
Keywords
Mume Fructus water extract; antibacterial effect; salmonellosis; Salmonella typhimurium;
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