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Ecotoxicological Effects of $CeO_2$ Nanoparticles on Soil Nematode Caenorhabditis elegans  

Roh, Ji-Yeon (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
Park, Young-Kwon (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
Choi, Jin-Hee (Faculty of Environmental Engineering, College of Urban Science, University of Seoul)
Publication Information
Environmental Analysis Health and Toxicology / v.23, no.2, 2008 , pp. 87-91 More about this Journal
Abstract
In this study, three different sizes of cerium oxide ($CeO_2$) nanoparticles were synthesized and exposed to Caenorhabditis elegans to investigate the potential harmful effect of $CeO_2$ nanoparticles on the environment. The effects of the $CeO_2$ nanoparticles on C. elegans were assessed at multiple levels, such as with respect to stress response gene expression, growth, reproduction and mortality. Moreover, to test the ecotoxicological relevance of $CeO_2$-induced gene expression. The overall results suggest that $CeO_2$ nanoparticles may provoke ecotoxicity in C. elegans especially with respect to gene expression, reproduction and survival, which can comprise an important contribution to knowledge on the ecotoxicity of $CeO_2$ nanoparticles, about which little data are available. This is particularly valuable in the biomarker research on ecotoxicology, as ecological relevance is a crucial criterion for the applicability of the biomarker in field biomonitoring and ecological risk assessment.
Keywords
ceria; Caenorhabditis elegans; stress related gene expression;
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