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Toxicity Assessment of PFOA and PFOS Using Freshwater Flea Hyalella azteca  

Lee, Chul-Woo (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Kim, Hyun-Mi (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Choi, Kyung-Hee (Environmental Exposure Assessment Division, National Institute of Environmental Research)
Publication Information
Environmental Analysis Health and Toxicology / v.22, no.3, 2007 , pp. 271-277 More about this Journal
Abstract
Perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) are fully flurorinated organic compounds which are highly persistent in environment and accumulated in organism. These chemicals are released to the environment at their manufacture, during their use in industrial and consumer applications and from disposal after their use. The purpose of this study was to determine the effects of PFOA and PFOS on the freshwater flea (Moina macrocopa). Acute toxicity test and chronic toxicity test were performed for 2 days and 10 days, respectively. Acute toxicity was assessed on the basis of mortality, while chronic toxicity was assessed by fecundity as well as mortality. The acute toxicity studies on PFOA and PFOS showed that the values of $LC_{50}$ were $73.9\;mg/L\;and\;27.7\;mg/L$ respectively. In the chronic toxicity test, fecundity was reduced significantly at 24.1 mg/L of PFOA and 9.3 mg/L of PFOS, respectively. Conclusively, the results of this work suggest that Moina macrocopa could be a suitable model organism for screening and assessing of environmental pollutants in water.
Keywords
perfluorooctanoic acid (PFOA); perfluorooctane sulfonate (PFOS); Moina macrocopa;
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  • Reference
1 EC. European Union Risk Assessment Report, Bis (pentabromodiphenyl) ether. European Commission, Joint Research Centre, EUR 20402 EN: 2002
2 Karrman A, van Bavel B, Jarnberg U, Hardell L and Lindstrom G. Perfluorinated chemicals in relation to other persistent organic pollutants in human blood, Chemosphere 2006; 64(9): 1582-1591   DOI   ScienceOn
3 Martin JW, Mabury SA, Solomon KR and Muir D. Dietary accumulation of perfluorinated acids in juvenile rainbow trout (Oncorhynchus mykiss), Environ Toxicol Chem 2003; 22(1): 189-195   DOI
4 Mawn MP, McKay RG, Ryan TW, Szostek B, Powley CR and Buck RC. Determination of extractable perfluorooctanoic acid (PFOA) in water, sweat simulant, saliva simulant, and methanol from textile and carpet samples by LC/MS/MS, Analyst 2005; 30 (5): 670-678
5 Sasaki K, Harada K, Saito N, Tsutsui T, Nakanishi S, Tsuzuki H and Koizumi A. Impact of airborne perfluorooctane sulfonate on the human body burden and the ecological system, Bull Environ Contam Toxicol 2003; 71: 408-413   DOI
6 Hoff PT, Van de Vijver K, Van Dongen W, Esmans EL, Blust R and De Coen WM. Perfluorooctane sulfonic acid in bib (Trisopterus luscus) and plaice Pleuronectes platessa) from the Western Scheldt and the Belgian North Sea: distribution and biochemical effects, Environ Toxicol Chem 2003a; 22(3): 608-614   DOI
7 Saito N, Sasaki K, Nakatome K, Harada K, Yoshinga T and Koizumi A. Perfluorooctane sulfonate concentrations in surface water in Japan, Arch Environ Contam Toxicol 2003; 45: 149-158   DOI
8 Garcia GG, Nandini S and Sarma SS. Effect of cadmium on the population dynamics of Moina macrocopa and Macrothrix triserialis (Cladocera), Bull Environ Contam Toxicol 2004; 72(4): 717-724
9 OECD. Hazard Assessment of Perfluorooctane Sulfonate (PFOS) and its Salts. ENV/JM/RD (2002)17/FINAL. Perfluoroalkylated Substances-Aquatic Environmental Assessment, RIKZ and University of Amsterdam. Report RIKZ/2002.043, 2002
10 US EPA. Methods for measuring the acute toxicity of effluents and receiving waters to freshwater and marine organisms, 5th ed. EPA Office of water (4303T) 2002
11 Renner R. Perfluorinated chemicals in blood, Environ Sci Technol 2006; 40(7): 2128-2134   DOI   ScienceOn
12 Begley TH, White K, Honigfort P, Twaroski ML, Neches R and Walker RA. Perfluorochemicals: potential sources of and migration from food packaging, Food Addit Contam 2005; 22(10): 1023-1031   DOI   ScienceOn
13 Brook D, Footitt A and Nwaogu TA. Environmental risk evaluation report: PFOS. UK Environmental Agency 2004
14 Boudreau TM, Wilson CJ, Cheong WJ, Sibley PK, Mabury SA Muir D and Solomon KR. Response of the zooplankton community and environmental fate of perfluorooctane sulfonic acid in aquatic microcosms, Environ Toxicol Chem 2003b; 22(11): 2739-2745   DOI   ScienceOn
15 Hoff PT, Van Dongen W, Esmans EL, Blust R and De Coen WM. Evaluation of the toxicological effects of perfluorooctane sulfonic acid in the common carp (Cyprinus carpio), Aquatic Toxicol 2003b; 62: 349-359   DOI   ScienceOn
16 Boudreau TM, Sibley PK, Mabury SA, Muir D and Solomon KR. Laboratory evaluation of the toxicity of perfluorooctane sulfonate (PFOS) on Selenastrum capricornutum, Chlorella vulgaris, Lemna gibba, Daphnia magna and Daphnia pulicaria, Arch Environ Contam Toxicol 2003a; 44: 307-313   DOI
17 Peden-Adams MM, EuDaly JG, Dabra S, EuDaly A, Heesemann L, Smythe J and Keil DE. Suppression of humoral immunity following exposure to the perfluori-nated insecticide sulfluramid, J Toxicol Environ Health A 2007; 70(13): 1130-1141   DOI   ScienceOn
18 Inoue K, Okada F, Ito R, Kato S, Sasaki S, Nakajima S, Uno A, Saijo Y, Sata F, Yoshimura Y, Kishi R and Nakazawa H. Perfluorooctane sulfonate (PFOS) and related perfluorinated compounds in human maternal and cord blood samples: assessment of PFOS exposure in a susceptible population during pregnancy, Environ Health Perspect 2004; 112(11): 1204-1207   DOI   ScienceOn
19 Renner R. Concerns over common perfluorinated surfactant, Environ Sci Technol 2003; 37(11): 201-202   DOI   ScienceOn
20 Nakayama S, Harada K, Inoue K, Sasaki K, Seery B, Saito N and Koizumi A. Distributions of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) in Japan and their toxicities, Environ Sci 2005; 12(6): 293-313